SCHEMBL6251908

SCHEMBL6251908

CCCCCCCCc1ccc(-c2cnc(-c3ccc(COC(CCCCCC)C(F)(F)F)cc3)nc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.51
ALDH1A1 P00352 3/20 0.51
RAB9A P51151 3/20 0.51
HSD17B10 Q99714 3/20 0.51
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
SMN1; SMN2 Q16637 2/20 0.51
KDM4E B2RXH2 2/20 0.51
USP2 O75604 1/20 0.51
GAA P10253 1/20 0.51
HPGD P15428 1/20 0.51
RARB P10826 6/20 0.43
RARA P10276 1/20 0.39
MTOR P42345 1/20 0.39
NPC1 O15118 1/20 0.39
STAT3 P40763 1/20 0.39
ATM Q13315 1/20 0.39
S1PR4 O95977 4/20 0.37
S1PR1 P21453 4/20 0.37
S1PR5 Q9H228 4/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6255691 1.00 MAPT (0.51) MAPTALDH1A1RAB9AHSD17B10MEN1
SCHEMBL6256073 0.98 MAPT (0.51) MAPTALDH1A1RAB9AHSD17B10MEN1
SCHEMBL8757828 0.93 RAB9A (0.50) MAPTALDH1A1RAB9AHSD17B10MEN1
SCHEMBL6251962 0.89 RAB9A (0.45) MAPTALDH1A1RAB9AHSD17B10MEN1
SCHEMBL6250654 0.87 MAPT (0.42) MAPTALDH1A1RAB9AHSD17B10MEN1
SCHEMBL30494129 0.85 BDKRB2 (0.41) MAPTALDH1A1HSD17B10MEN1KMT2A
SCHEMBL8860918 0.81 RAB9A (0.49) MAPTALDH1A1RAB9AHSD17B10MEN1
SCHEMBL7863568 0.80 RAB9A (0.48) MAPTALDH1A1RAB9AHSD17B10MEN1
SCHEMBL8860721 0.80 RAB9A (0.48) MAPTALDH1A1RAB9AHSD17B10MEN1
SCHEMBL8860737 0.80 RAB9A (0.48) MAPTALDH1A1RAB9AHSD17B10MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0884309-B1 Optically active compound, antiferroelectric liquid crystal composition containing the same, process for producing the same and process for producing optically active carboxylic acid SEMICONDUCTOR ENERGY LAB (JP) 2005-09-07 EP claimed
EP-0884309-B1 Optically active compound, antiferroelectric liquid crystal composition containing the same, process for producing the same and process for producing optically active carboxylic acid SEMICONDUCTOR ENERGY LAB (JP) 2005-09-07 EP disclosed
US-5965059-A Optically active compound, antiferroelectric liquid crystal composition containing the same, process for producing the same and process for producing an optically active carboxylic acid TAKASAGO INTERNATIONAL CORPORATION (JP) 1999-10-12 US disclosed
EP-0884309-A1 Optically active compound, antiferroelectric liquid crystal composition containing the same, process for producing the same and process for producing optically active carboxylic acid Takasago International Corporation (JP) 1998-12-16 EP disclosed