SCHEMBL6252200

SCHEMBL6252200

CC(CC(=O)O)C(=O)OC(C)C(F)(F)F

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.32
ALDH1A1 P00352 1/20 0.30
SLC22A6 Q4U2R8 1/20 0.30
LMNA P02545 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL107672 0.80 CA1 (0.31)
SCHEMBL28014447 0.78 HDAC1 (0.38)
SCHEMBL8980093 0.77 TSHR (0.40) ALOX15SLC22A6LMNASMN1; SMN2
SCHEMBL12095053 0.77 TSHR (0.32)
SCHEMBL701889 0.77 TSHR (0.32)
SCHEMBL17264841 0.74 GABRA1 (0.31)
SCHEMBL16369127 0.74
SCHEMBL2607995 0.74
SCHEMBL11865413 0.72 MAPT (0.41) ALOX15SLC22A6LMNASMN1; SMN2
SCHEMBL11212251 0.72 SLC22A6 (0.39) ALOX15SLC22A6LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024025741-A1 POLYPROPYLENE COMPOSITIONS WITH ENHANCED STRAIN HARDENING AND METHODS OF PRODUCING SAME EXXONMOBIL CHEMICAL PATENTS INC. (US) 2024-02-01 WO disclosed
EP-4107196-A1 PROPYLENE-BASED POLYMER COMPOSITIONS HAVING A HIGH MOLECULAR WEIGHT TAIL ExxonMobil Chemical Patents Inc. (US) 2022-12-28 EP disclosed
CN-110785442-B High melt strength polypropylene with high stiffness and clarity 埃克森美孚化学专利公司 2022-05-13 CN disclosed
CN-114230931-A High melt strength polypropylene and extrusion process for maintaining melt strength 埃克森美孚化学专利公司 2022-03-25 CN disclosed
EP-3630852-A1 HIGH MELT STRENGTH POLYPROPYLENE WITH HIGH STIFFNESS AND CLARITY ExxonMobil Chemical Patents Inc. (US) 2020-04-08 EP disclosed
CN-110785442-A High melt strength polypropylene with high stiffness and clarity 埃克森美孚化学专利公司 2020-02-11 CN disclosed
WO-2018222310-A1 HIGH MELT STRENGTH POLYPROPYLENE WITH HIGH STIFFNESS AND CLARITY EXXONMOBIL CHEMICAL PATENTS INC. (US) 2018-12-06 WO disclosed
EP-2914637-A1 BROAD MOLECULAR WEIGHT DISTRIBUTION POLYPROPYLENE RESINS ExxonMobil Chemical Patents Inc. (US) 2015-09-09 EP disclosed
WO-2015012963-A1 METHODS FOR POLYOLEFIN POLYMERIZATION WITH HIGH ACTIVITY CATALYST SYSTEMS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2015-01-29 WO disclosed
WO-2014070386-A1 BROAD MOLECULAR WEIGHT DISTRIBUTION POLYPROPYLENE RESINS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2014-05-08 WO disclosed
EP-1525231-A1 CATALYST SYSTEM FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia S.P.A. (IT) 2005-04-27 EP disclosed
WO-2004005359-A1 CATALYST SYSTEM FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2004-01-15 WO disclosed