Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 12/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 11/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | NAPEPLD | Q6IQ20 | 3/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | TPH1 | P17752 | 1/20 | 0.34 |
| ▸ | STAT6 | P42226 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6250215 | 0.91 | OPRK1 (0.50) | OPRK1CYP2D6NAPEPLD | |
| SCHEMBL6250186 | 0.87 | OPRK1 (0.57) | OPRK1CYP2D6OPRM1OPRD1 | |
| SCHEMBL6247456 | 0.86 | OPRK1 (0.54) | OPRK1CYP2D6OPRM1OPRD1 | |
| SCHEMBL6250833 | 0.86 | OPRK1 (0.54) | OPRK1CYP2D6 | |
| SCHEMBL6248817 | 0.86 | OPRK1 (0.54) | OPRK1CYP2D6 | |
| SCHEMBL6250179 | 0.86 | OPRK1 (0.55) | OPRK1CYP2D6 | |
| SCHEMBL6249594 | 0.85 | OPRK1 (0.55) | OPRK1CYP2D6 | |
| SCHEMBL6247648 | 0.84 | OPRK1 (0.57) | OPRK1CYP2D6OPRM1OPRD1 | |
| SCHEMBL6249600 | 0.82 | CYP2D6 (0.56) | OPRK1CYP2D6 | |
| SCHEMBL6250180 | 0.81 | OPRK1 (0.58) | OPRK1CYP2D6NAPEPLDOPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005049564-A1 | AMIDE DERIVATIVES AND METHODS OF THEIR USE | ADOLOR CORPORATION (US) | 2005-06-02 | — | — | WO | disclosed |