Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 5/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | VNN1 | O95497 | 1/20 | 0.41 |
| ▸ | VCP | P55072 | 1/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.40 |
| ▸ | MELK | Q14680 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2250766 | 0.93 | FYN (0.53) | FYNPIM1PIM2VCPMAPT | |
| SCHEMBL1945954 | 0.89 | FYN (0.56) | FYNPIM1PIM2VCPIRAK4 | |
| SCHEMBL1946517 | 0.84 | FYN (0.66) | FYNPIM1PIM2VCPIRAK4 | |
| SCHEMBL625324 | 0.83 | MAPT (0.42) | PIM1MELKMAPTTHRBNPC1 | |
| SCHEMBL1945872 | 0.83 | FYN (0.47) | FYNPIM1PIM2MAPTTHRB | |
| SCHEMBL1946038 | 0.83 | FYN (0.68) | FYNPIM1PIM2SMN1; SMN2 | |
| SCHEMBL623807 | 0.81 | ALDH1A1 (0.40) | FYNPIM1PIM2MAP4K4MAPT | |
| SCHEMBL625256 | 0.81 | FYN (0.72) | FYNPIM1PIM2 | |
| SCHEMBL1944937 | 0.80 | FYN (0.51) | FYNMAP4K4MAPTNPC1RAB9A | |
| SCHEMBL625205 | 0.80 | F2RL3 (0.53) | FYNPIM1VCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020217-A1 | AMINO- IMIDAZOLOTHIADIAZOLES FOR USE AS PROTEIN OR LIPID KINASE INHIBITORS | CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) (ES) | 2012-02-16 | — | — | WO | disclosed |