Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 12/20 | 0.40 |
| ▸ | RARA | P10276 | 10/20 | 0.40 |
| ▸ | RARG | P13631 | 10/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6250578 | 0.89 | RARA (0.41) | RARBRARARARGRXRANR2E1 | |
| SCHEMBL4491751 | 0.85 | RARB (0.48) | RARBRARARARGRXRANR2E1 | |
| SCHEMBL4497657 | 0.80 | RARB (0.48) | RARBRARARARGRXRANR2E1 | |
| SCHEMBL4509207 | 0.75 | RARB (0.44) | RARBRARARARG | |
| SCHEMBL5707360 | 0.73 | RARB (0.50) | RARBRARARARGRXRANR2E1 | |
| SCHEMBL4503989 | 0.72 | RARB (0.66) | RARBRARARARGRXRANR2E1 | |
| SCHEMBL6247945 | 0.72 | RARB (0.47) | RARBRARARARGRXRANR2E1 | |
| SCHEMBL3897864 | 0.72 | RARB (0.50) | RARBRARARARGRXRANR2E1 | |
| SCHEMBL4506863 | 0.72 | RARB (0.48) | RARBRARARARGRXRANR2E1 | |
| SCHEMBL6250586 | 0.71 | RARB (0.42) | RARBRARARARGRXRANR2E1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1565433-A2 | NOVEL LIGANDS THAT ARE ANTAGONISTS OF RAR RECEPTORS, PROCESS FOR PREPARING THEM AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | Galderma Research & Development, S.N.C. (FR) | 2005-08-24 | — | — | EP | disclosed |
| WO-2004046096-A2 | NOVEL LIGANDS THAT ARE ANTAGONISTS OF RAF RECEPTORS, PROCESS FOR PREPARING THEM AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | GALDERMA RESEARCH & DEVELOPMENT,S.N.C. (FR) | 2004-06-03 | — | — | WO | disclosed |