Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL3 | Q96RI0 | 3/20 | 0.38 |
| ▸ | PIM3 | Q86V86 | 4/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.37 |
| ▸ | CDK9 | P50750 | 1/20 | 0.37 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.37 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 7/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 3/20 | 0.36 |
| ▸ | FLT3 | P36888 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL625496 | 0.86 | PIM1 (0.39) | F2RL3PIM3CDK9TYRO3IRAK4 | |
| SCHEMBL625561 | 0.86 | PIM1 (0.49) | F2RL3PIM3TYRO3PIM1KCNH2 | |
| SCHEMBL623722 | 0.85 | PIM1 (0.43) | F2RL3PIM3TYRO3IRAK4PIM1 | |
| SCHEMBL625490 | 0.85 | PIM1 (0.39) | F2RL3PIM3PIM1KCNH2PIM2 | |
| SCHEMBL625295 | 0.84 | FYN (0.49) | PIM3PIM1KCNH2PIM2FLT3 | |
| SCHEMBL624837 | 0.81 | PIM1 (0.47) | F2RL3PIM3PIM1KCNH2PIM2 | |
| SCHEMBL623435 | 0.80 | PIM1 (0.46) | F2RL3PIM3PIM1KCNH2PIM2 | |
| SCHEMBL1945312 | 0.79 | FYN (0.45) | F2RL3PIM1KCNH2PIM2FLT3 | |
| SCHEMBL1944061 | 0.78 | PIM1 (0.54) | F2RL3PIM3PIM1KCNH2PIM2 | |
| SCHEMBL626259 | 0.78 | PIM1 (0.53) | F2RL3CCNT1PIM1KCNH2PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020217-A1 | AMINO- IMIDAZOLOTHIADIAZOLES FOR USE AS PROTEIN OR LIPID KINASE INHIBITORS | CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) (ES) | 2012-02-16 | — | — | WO | disclosed |