Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 17/20 | 0.53 |
| ▸ | PIM2 | Q9P1W9 | 3/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | F2RL3 | Q96RI0 | 2/20 | 0.42 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1944061 | 0.92 | PIM1 (0.54) | PIM1PIM2KCNH2FLT3F2RL3 | |
| SCHEMBL1945312 | 0.91 | FYN (0.45) | PIM1PIM2KCNH2FLT3F2RL3 | |
| SCHEMBL625292 | 0.89 | PIM1 (0.53) | PIM1PIM2KCNH2FLT3F2RL3 | |
| Hydrochloric Acid SCHEMBL625023 | 0.88 | PIM1 (0.45) | PIM1PIM2KCNH2FLT3F2RL3 | |
| SCHEMBL623435 | 0.88 | PIM1 (0.46) | PIM1PIM2KCNH2FLT3F2RL3 | |
| SCHEMBL625501 | 0.85 | PIM1 (0.43) | PIM1PIM2KCNH2FLT3F2RL3 | |
| SCHEMBL623873 | 0.82 | IDH1 (0.44) | PIM1KCNH2CCNT1 | |
| SCHEMBL625561 | 0.81 | PIM1 (0.49) | PIM1PIM2KCNH2FLT3F2RL3 | |
| SCHEMBL1945253 | 0.81 | PIM1 (0.47) | PIM1PIM2KCNH2FLT3F2RL3 | |
| SCHEMBL626258 | 0.80 | PIM1 (0.68) | PIM1PIM2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020217-A1 | AMINO- IMIDAZOLOTHIADIAZOLES FOR USE AS PROTEIN OR LIPID KINASE INHIBITORS | CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) (ES) | 2012-02-16 | — | — | WO | disclosed |