Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.45 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.45 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.45 |
| ▸ | KCNB1 | Q14721 | 1/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 5/20 | 0.41 |
| ▸ | CFD | P00746 | 1/20 | 0.41 |
| ▸ | CTSV | O60911 | 2/20 | 0.40 |
| ▸ | CTSL | P07711 | 2/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6255101 | 0.89 | ERAP2 (0.45) | ERAP2ERAP1LNPEPKCNB1KDM4C | |
| SCHEMBL6254034 | 0.88 | CYP3A4 (0.50) | ERAP2ERAP1LNPEPKCNB1KDM4C | |
| SCHEMBL5360875 | 0.87 | PTPN11 (0.44) | ERAP2ERAP1LNPEPKCNB1KDM4C | |
| SCHEMBL6251972 | 0.80 | MEN1 (0.44) | HCAR2CTSVCTSLMEN1RECQL | |
| SCHEMBL5360954 | 0.78 | ALOX15 (0.42) | ERAP2ERAP1LNPEPKCNB1MEN1 | |
| SCHEMBL5365598 | 0.78 | PTPN11 (0.41) | ERAP2ERAP1LNPEPKCNB1KDM4C | |
| SCHEMBL5362814 | 0.76 | KCNB1 (0.42) | ERAP2ERAP1LNPEPKCNB1MEN1 | |
| SCHEMBL5359635 | 0.74 | AOC3 (0.50) | HCAR2AOC3SIRT2 | |
| SCHEMBL5361015 | 0.73 | KCNB1 (0.44) | ERAP2ERAP1LNPEPKCNB1AOC3 | |
| SCHEMBL5374067 | 0.73 | LTB4R2 (0.42) | MEN1RECQLBLMKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572629-A1 | COMPOUNDS WHICH MODULATE PPARϝ TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | Galderma Research & Development, S.N.C. (FR) | 2005-09-14 | — | — | EP | claimed |
| WO-2004052840-A1 | COMPOUNDS WHICH MODULATE PPARϜ TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-06-24 | — | — | WO | claimed |