Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 17/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 7/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3924003 | 0.83 | ADRB2 (0.49) | ADRB2ADRB1NPC1ALDH1A1POLB | |
| SCHEMBL13840715 | 0.83 | ADRB2 (0.49) | ADRB2ADRB1NPC1ALDH1A1POLB | |
| SCHEMBL4393362 | 0.83 | ADRB2 (0.67) | ADRB2ADRB1CYP1A2 | |
| SCHEMBL4393355 | 0.83 | ADRB2 (0.67) | ADRB2ADRB1CYP1A2 | |
| SCHEMBL4388108 | 0.76 | ADRB2 (0.61) | ADRB2ADRB1CYP1A2 | |
| SCHEMBL4388116 | 0.76 | ADRB2 (0.61) | ADRB2ADRB1CYP1A2 | |
| SCHEMBL5968688 | 0.76 | ADRB2 (0.65) | ADRB2ADRB1CYP1A2 | |
| SCHEMBL5968691 | 0.76 | ADRB2 (0.65) | ADRB2ADRB1CYP1A2 | |
| SCHEMBL11692760 | 0.76 | ADRB2 (0.58) | ADRB2ADRB1 | |
| SCHEMBL13840696 | 0.75 | NPC1 (0.47) | ADRB2ADRB1NPC1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1577291-A1 | Phenylethanolamine derivatives as beta-2 agonists | Pfizer Limited (GB) | 2005-09-21 | — | — | EP | disclosed |