Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.49 |
| ▸ | MME | P08473 | 6/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.43 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2633846 | 0.98 | ACE (0.47) | ACEMMEKDM4EMAPTTHRB | |
| SCHEMBL4363673 | 0.91 | ACE (0.58) | ACEMMEKDM4EMAPTTHRB | |
| SCHEMBL8216927 | 0.91 | ACE (0.58) | ACEMMEKDM4EMAPTTHRB | |
| SCHEMBL321602 | 0.91 | ACE (0.58) | ACEMMEKDM4EMAPTTHRB | |
| SCHEMBL6009831 | 0.89 | TGFBR1 (0.52) | ACEMMETGFBR1OR51E2FOLH1 | |
| SCHEMBL7070376 | 0.89 | TGFBR1 (0.52) | ACEMMETGFBR1OR51E2FOLH1 | |
| SCHEMBL5424761 | 0.82 | KDM4E (0.69) | ACEMMEKDM4EMAPTTHRB | |
| SCHEMBL29569220 | 0.79 | ACE (0.54) | ACEMMEKDM4EMAPTTHRB | |
| SCHEMBL30945534 | 0.78 | ACE (0.45) | ACEMMEKDM4EMAPTTHRB | |
| SCHEMBL5967479 | 0.78 | ACE (0.45) | ACEMMEKDM4EMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005056572-A2 | CLUSTERED MULTI-ANTIGENIC CARBOHYDRATE CONSTRUCTS, METHODS FOR THEIR PREPARATION AND USES THEREOF | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2005-06-23 | — | — | WO | disclosed |