SCHEMBL321602

SCHEMBL321602

O=C(NC(CS)C(=O)O)C(O)CO

nearest known ligand 0.58

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ACE P12821 1/20 0.58
KDM4E B2RXH2 1/20 0.53
MAPT P10636 1/20 0.53
THRB P10828 1/20 0.53
ALOX15 P16050 1/20 0.53
NFKB1 P19838 1/20 0.53
PTGS2 P35354 1/20 0.53
THPO P40225 1/20 0.53
RECQL P46063 1/20 0.53
BLM P54132 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
FOLH1 Q04609 1/20 0.46
OR51E2 Q9H255 1/20 0.44
MME P08473 7/20 0.44
TGFBR1 P36897 3/20 0.38
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4363673 1.00 ACE (0.58) ACEKDM4EMAPTTHRBALOX15
SCHEMBL8216927 1.00 ACE (0.58) ACEKDM4EMAPTTHRBALOX15
SCHEMBL6253538 0.91 ACE (0.49) ACEKDM4EMAPTTHRBALOX15
SCHEMBL2633846 0.89 ACE (0.47) ACEKDM4EMAPTTHRBALOX15
SCHEMBL7070376 0.85 TGFBR1 (0.52) ACEFOLH1OR51E2MMETGFBR1
SCHEMBL6009831 0.85 TGFBR1 (0.52) ACEFOLH1OR51E2MMETGFBR1
SCHEMBL8491732 0.80 OR51E2 (0.44) ACEFOLH1OR51E2MMETGFBR1
SCHEMBL29837094 0.80 OR51E2 (0.44) ACEKDM4EMAPTTHRBALOX15
SCHEMBL28806122 0.80 OR51E2 (0.44) ACEKDM4EMAPTTHRBALOX15
SCHEMBL8491734 0.80 OR51E2 (0.44) ACEFOLH1OR51E2MMETGFBR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 124 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3377099-A1 ADJUVANTING SYSTEMS AND WATER-FREE VACCINE COMPOSITIONS COMPRISING A POLYI:C POLYNUCLEOTIDE ADJUVANT AND A LIPID-BASED ADJUVANT ImmunoVaccine Technologies Inc. (CA) 2018-09-26 EP claimed
CN-108430505-A The auxiliary system of adjuvant including polyinosinic acid polynucleotides adjuvant and based on lipid and anhydrous vaccine composition 免疫疫苗技术有限公司 2018-08-21 CN claimed
WO-2012078116-A1 IMMUNOGENIC CHIKUNGUNYA VIRUS PEPTIDES AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2012-06-14 WO claimed
EP-4144368-B1 RSV IMMUNIZATION REGIMEN GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2025-02-26 EP disclosed
EP-3527224-B1 RSV IMMUNIZATION REGIMEN GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2025-02-26 EP disclosed
US-20250042951-A1 PRE-FUSION RSV F ANTIGENS NOVARTIS AG (CH) 2025-02-06 US disclosed
US-12139512-B2 Pre-fusion RSV F antigens GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2024-11-12 US disclosed
US-20240299527-A1 RSV IMMUNIZATION REGIMEN NOVARTIS AG (CH) 2024-09-12 US disclosed
EP-4183412-B1 RSV F PROTEIN COMPOSITIONS AND METHODS FOR MAKING SAME GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2024-08-14 EP disclosed
US-20240239845-A1 PRE-FUSION RSV F ANTIGENS NOVARTIS AG (CH) 2024-07-18 US disclosed
US-20240034773-A1 RSV F PROTEIN COMPOSITIONS AND METHODS FOR MAKING SAME GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2024-02-01 US disclosed
WO-2001036488-A1 ANTIBODY AGAINST THE HUMAN TOLL-LIKE RECEPTOR-2 (TLR2) AND USES THEREOF LEIV EIRIKSSON NYFOTEK AS (NO) 2001-05-25 WO disclosed
US-6074650-A INDUCTION OF CYTOTOXIC LYMPHOCYTES HOECHST AKTIENGESELLSCHAFT (DE) 2000-06-13 US disclosed
US-6024964-A ANTIBODIES AND ANTIGENS WITH MEMBRANE ANCHORING HOECHST AKTIENGESELLSCHAFT (DE) 2000-02-15 US disclosed
EP-0210412-B1 Anchoring membrane ingredient conjugate, and its use HOECHST AG (DE) 1995-12-13 EP disclosed
WO-1995005454-A1 ENGINEERED BACTERIOPHAGES AND VACCINES CONTAINING THEM CAMBRIDGE BACTERIOPHAGE TECHNOLOGIES LTD. (GB) 1995-02-23 WO disclosed
EP-0114787-B1 PEPTIDE DERIVATIVES CIBA-GEIGY AG (CH) 1991-09-25 EP disclosed
EP-0210412-A2 Anchoring membrane ingredient conjugate, and its use HOECHST AKTIENGESELLSCHAFT (DE) 1987-02-04 EP disclosed
EP-0114787-A2 Peptide derivatives CIBA-GEIGY AG (CH) 1984-08-01 EP disclosed
US-4439425-A IMMUNOLOGY CIBA-GEIGY CORPORATION (US) 1984-03-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250042951-A1 PRE-FUSION RSV F ANTIGENS FURIN, CD69, LY96 ACE 754/4885KDM4E 4596/4885MAPT 1260/4885
US-12139512-B2 Pre-fusion RSV F antigens FURIN, CD69, LY96 ACE 754/4885KDM4E 4596/4885MAPT 1260/4885
US-20240299527-A1 RSV IMMUNIZATION REGIMEN IL5, IL15, IFNG ACE 1308/4885KDM4E 4652/4885MAPT 2978/4885
US-20240239845-A1 PRE-FUSION RSV F ANTIGENS FURIN, CD69, LY96 ACE 754/4885KDM4E 4596/4885MAPT 1260/4885
US-20240034773-A1 RSV F PROTEIN COMPOSITIONS AND METHODS FOR MAKING SAME RNASEL, TIMCC, RNGTT ACE 1093/4885KDM4E 4397/4885MAPT 1801/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.