SCHEMBL6253785

SCHEMBL6253785

CCCCCCC1=CCC(C)=C1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 4/20 0.38
CYP3A4 P08684 2/20 0.35
ACHE P22303 2/20 0.35
LIPG Q9Y5X9 1/20 0.35
BACE1 P56817 1/20 0.35
CYP19A1 P11511 1/20 0.35
ESR1 P03372 2/20 0.34
ADRA2A P08913 2/20 0.34
ADORA3 P0DMS8 2/20 0.34
TACR2 P21452 2/20 0.34
SLC6A2 P23975 2/20 0.34
SLC6A4 P31645 2/20 0.34
SLC6A3 Q01959 2/20 0.34
KCNH2 Q12809 2/20 0.34
KDM4E B2RXH2 1/20 0.34
ALDH1A1 P00352 1/20 0.34
LMNA P02545 1/20 0.34
SHBG P04278 1/20 0.34
TP53 P04637 1/20 0.34
HSPD1 P10809 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6250287 1.00 PTGS2 (0.38) PTGS2CYP3A4ACHELIPGBACE1
SCHEMBL6253058 1.00 PTGS2 (0.38) PTGS2CYP3A4ACHELIPGBACE1
Hydrochloric Acid SCHEMBL8397551 0.98 PTGS2 (0.37) PTGS2CYP3A4ACHELIPGBACE1
SCHEMBL6250217 0.98 PTGS2 (0.36) PTGS2CYP3A4ACHELIPGBACE1
SCHEMBL1539590 0.92 NPC1 (0.36) CYP19A1KDM4E
SCHEMBL924997 0.92 NPC1 (0.36) CYP19A1KDM4E
SCHEMBL27988027 0.90 NPC1 (0.35) KDM4E
SCHEMBL27988016 0.90 NPC1 (0.35) KDM4E
Hydrochloric Acid SCHEMBL3802951 0.88 NPC1 (0.34)
SCHEMBL6303309 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0926150-B1 Production of alkali metal cyclopentadienylides and production of dihalobis(eta-substituted-cyclopentadienyl) zirconium from alkali metal cyclopentadienylides HONSHU CHEMICAL IND (JP) 2005-09-07 EP disclosed
US-6046346-A Production of alkali metal cyclopentadienylide and production of dihalobis (η-substituted-cyclopentadienyl) zirconium from alkali metal cyclopentadienylide HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2000-04-04 US disclosed
EP-0926150-A2 Production of alkali metal cyclopentadienylide and production of dihalobis(eta-substituted-cyclopentadienyl) zirconium from alkali metal cyclopentadienylide Honshu Chemical Industry Co. Ltd. (JP) 1999-06-30 EP disclosed