SCHEMBL924997

SCHEMBL924997

CCCCC1=CCC(C)=C1

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.36
HPGD P15428 1/20 0.36
MAPK1 P28482 1/20 0.36
HTT P42858 1/20 0.36
RAB9A P51151 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
SKP2 Q13309 1/20 0.33
KDM4E B2RXH2 1/20 0.31
PKM P14618 1/20 0.31
CYP19A1 P11511 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1539590 1.00 NPC1 (0.36) NPC1HPGDMAPK1HTTRAB9A
SCHEMBL29010373 0.98 NPC1 (0.35) NPC1HPGDMAPK1HTTRAB9A
SCHEMBL27988027 0.98 NPC1 (0.35) NPC1HPGDMAPK1HTTRAB9A
SCHEMBL27988016 0.98 NPC1 (0.35) NPC1HPGDMAPK1HTTRAB9A
Hydrochloric Acid SCHEMBL3802951 0.96 NPC1 (0.34) NPC1HPGDMAPK1HTTRAB9A
SCHEMBL6250217 0.94 PTGS2 (0.36) NPC1HPGDMAPK1HTTRAB9A
SCHEMBL6250287 0.92 PTGS2 (0.38) KDM4ECYP19A1
SCHEMBL6253058 0.92 PTGS2 (0.38) KDM4ECYP19A1
SCHEMBL6253785 0.92 PTGS2 (0.38) KDM4ECYP19A1
Hydrochloric Acid SCHEMBL8397551 0.90 PTGS2 (0.37) KDM4ECYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116410385-A Polyolefin elastomer, preparation method thereof and metallocene catalyst used in polyolefin elastomer 中国石油天然气股份有限公司 2023-07-11 CN claimed
WO-2013177284-A1 HAFNIUM-CONTAINING PRECURSORS FOR VAPOR DEPOSITION L'AIR LIQUIDE, SOCIETE ANONYME POUR L'ETUDE ET L'EXPLOITATION DES PROCEDES GEORGES CLAUDE (FR) 2013-11-28 WO claimed
WO-2013177292-A1 TITANIUM-CONTAINING PRECURSORS FOR VAPOR DEPOSITION L'AIR LIQUIDE, SOCIETE ANONYME POUR L'ETUDE ET L'EXPLOITATION DES PROCEDES GEORGES CLAUDE (FR) 2013-11-28 WO claimed
WO-2013177269-A2 ZIRCONIUM-CONTAINING PRECURSORS FOR VAPOR DEPOSITION L'AIR LIQUIDE, SOCIETE ANONYME POUR L'ETUDE ET L'EXPLOITATION DES PROCEDES GEORGES CLAUDE (FR) 2013-11-28 WO claimed
US-11766669-B2 Hexahydrocyclopenta[e]-as-indacen-1-yl and octahydrobenzo[e]-as-indacen-1-yl based catalyst complexes and process for use thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-09-26 US disclosed
CN-116410385-A Polyolefin elastomer, preparation method thereof and metallocene catalyst used in polyolefin elastomer 中国石油天然气股份有限公司 2023-07-11 CN disclosed
US-20210402384-A1 Hexahydrocyclopenta[e]-as-indacen-1-yl and Octahydrobenzo[e]-as-indacen-1-yl based Catalyst Complexes and Process for Use Thereof EXXONMOBIL CHEMICAL PATENTS INC. 2021-12-30 US disclosed
EP-2749579-B1 CONJUGATED DIENE POLYMER AND METHOD FOR PRODUCING SAME ZEON CORP (JP) 2017-11-15 EP disclosed
US-9745394-B2 Conjugated diene polymer and method for producing same ZEON CORPORATION (JP) 2017-08-29 US disclosed
EP-3026069-A1 RUTHENIUM COMPLEX Zeon Corporation (JP) 2016-06-01 EP disclosed
US-20160096910-A1 CONJUGATED DIENE POLYMER AND METHOD FOR PRODUCING SAME ZEON CORPORATION (JP) 2016-04-07 US disclosed
US-9243100-B2 Conjugated diene polymer and method for producing same ZEON CORPORATION (JP) 2016-01-26 US disclosed
US-6046346-A Production of alkali metal cyclopentadienylide and production of dihalobis (η-substituted-cyclopentadienyl) zirconium from alkali metal cyclopentadienylide HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2000-04-04 US disclosed
EP-0807143-B1 THERMOPLASTIC PROPYLENE ELASTOMERS AND ONE POT/TWO CATALYSTS PROCESS TO PRODUCE THEM EXXON CHEMICAL PATENTS INC (US) 2000-03-15 EP disclosed
US-5990272-A HEATING POLYOLEFIN CONTACTED WITH A LIGAND DECOMPOSER TO REMOVE DECOMPOSED METALLOCENE LIGANDS FROM THE POLYOLEFIN MITSUI CHEMICALS, INC. (JP) 1999-11-23 US disclosed
EP-0926150-A2 Production of alkali metal cyclopentadienylide and production of dihalobis(eta-substituted-cyclopentadienyl) zirconium from alkali metal cyclopentadienylide Honshu Chemical Industry Co. Ltd. (JP) 1999-06-30 EP disclosed
EP-0766704-B1 POLYMERIZATION PROCESS AND CATALYST SYSTEMS USEFUL THEREIN EXXON CHEMICAL PATENTS INC (US) 1998-12-23 EP disclosed
EP-0808850-A1 Method of treating polyolefin MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1997-11-26 EP disclosed
EP-0766704-A1 POLYMERIZATION PROCESS AND CATALYST SYSTEMS USEFUL THEREIN EXXON CHEMICAL PATENTS INC. (US) 1997-04-09 EP disclosed
WO-1996000246-A1 POLYMERIZATION PROCESS AND CATALYST SYSTEMS USEFUL THEREIN EXXON CHEMICAL PATENTS INC. (US) 1996-01-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160096910-A1 CONJUGATED DIENE POLYMER AND METHOD FOR PRODUCING SAME PCNA, TELO2, MSN NPC1 3536/4885HPGD 1844/4885MAPK1 605/4885
US-11766669-B2 Hexahydrocyclopenta[e]-as-indacen-1-yl and octahydrobenzo[e]-as-indacen-1-yl based catalyst complexes and process for use thereof MLX, ZYX, TXN NPC1 2588/4885HPGD 3285/4885MAPK1 3339/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.