SCHEMBL6254014

SCHEMBL6254014

CC[Zr](Cl)(Cl)(CC)(C1C(C)=Cc2c(-c3ccccc3)cccc21)(C1C(C)=Cc2c(-c3ccccc3)cccc21)[SiH](C)C

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PDCD1 Q15116 1/20 0.31
CD274 Q9NZQ7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6255445 0.86
SCHEMBL7719075 0.80 PDCD1 (0.32) PDCD1CD274
Trimethylammonium SCHEMBL7162626 0.79
SCHEMBL19460558 0.78 BCHE (0.31) PDCD1CD274
SCHEMBL8830685 0.77 PDCD1 (0.32) PDCD1CD274
SCHEMBL7643714 0.77 PDCD1 (0.32) PDCD1CD274
SCHEMBL7935166 0.77 PDCD1 (0.32) PDCD1CD274
SCHEMBL5067417 0.75 PDCD1 (0.33) PDCD1CD274
SCHEMBL796298 0.75 BCHE (0.31) PDCD1CD274
SCHEMBL2856357 0.75 PDCD1 (0.30) PDCD1CD274

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1106345-B1 Heat-sealable multilayer polyolefin films TOTAL PETROCHEMICALS RES FELUY (BE) 2005-09-07 EP disclosed
US-20050100752-A1 Heat-sealable films FINA TECHNOLOGY, INC. 2005-05-12 US disclosed
US-6641913-B1 Flexible substrate of crystalline thermoplastic polymer bonded to syndiotactic propylene polymer; packaging FINA TECHNOLOGY, INC. 2003-11-04 US disclosed
US-6579962-B1 Heat shrinkable film; isotactic polymer produced using such as racemic dimethylsilyl bis(2-methylindenyl)zirconium dichloride catalyst FINA TECHNOLOGY, INC. 2003-06-17 US disclosed
EP-1106345-A2 Heat-sealable multilayer polyolefin films FINA TECHNOLOGY, INC. (US) 2001-06-13 EP disclosed
US-6090325-A CHARACTERIZED BY A BRIDGED RACEMIC BIS(INDENYL) LIGAND SUBSTITUTED AT THE PROXIMAL POSITION. FINA TECHNOLOGY, INC. (US) 2000-07-18 US disclosed
EP-0905173-A1 Biaxially-oriented metallocene-based polypropylene films FINA TECHNOLOGY, INC. (US) 1999-03-31 EP disclosed