Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7078536 | 0.90 | EDNRB (0.30) | — | |
| SCHEMBL7935166 | 0.85 | PDCD1 (0.32) | PDCD1CD274CYP2A6CHRNB2CHRNA4 | |
| SCHEMBL7719075 | 0.85 | PDCD1 (0.32) | PDCD1CD274CYP2A6CHRNB2CHRNA4 | |
| SCHEMBL7643714 | 0.85 | PDCD1 (0.32) | PDCD1CD274CYP2A6CHRNB2CHRNA4 | |
| SCHEMBL6242940 | 0.85 | BRD4 (0.32) | — | |
| SCHEMBL7130806 | 0.84 | KIF11 (0.35) | — | |
| SCHEMBL5067417 | 0.84 | PDCD1 (0.33) | PDCD1CD274CHRNB2CHRNA4HTR1A | |
| SCHEMBL2856357 | 0.83 | PDCD1 (0.30) | PDCD1CD274 | |
| SCHEMBL6242041 | 0.82 | HTR1A (0.33) | CYP2A6HTR1AHTR7 | |
| SCHEMBL5352550 | 0.80 | PDCD1 (0.30) | PDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5597881-A | PRODUCING THIN-WALLED INJECTION MOLDINGS USING ISOTACTIC HIGH MOLECULAR WEIGHT POLYOLEFINS, SUCH AS PROPYLENE HOMOPOLYMERS AND COPOLYMERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-01-28 | — | — | US | disclosed |