Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 3/20 | 0.31 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.31 |
| ▸ | HTR1A | P08908 | 2/20 | 0.31 |
| ▸ | HTR7 | P34969 | 2/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7935166 | 0.90 | PDCD1 (0.32) | PDCD1CD274CHRNB2CHRNA4HTR2B | |
| SCHEMBL6065657 | 0.90 | EDNRB (0.31) | — | |
| SCHEMBL5352550 | 0.87 | PDCD1 (0.30) | PDCD1CD274 | |
| SCHEMBL7597789 | 0.87 | PDCD1 (0.30) | PDCD1CD274 | |
| SCHEMBL6065482 | 0.86 | EDNRB (0.34) | — | |
| SCHEMBL6065619 | 0.85 | BRD4 (0.32) | BRD4 | |
| SCHEMBL7878211 | 0.84 | PDCD1 (0.31) | PDCD1CD274 | |
| SCHEMBL5359557 | 0.84 | GSTP1 (0.36) | CHRNB2CHRNA4 | |
| SCHEMBL6065066 | 0.84 | CYP11B1 (0.34) | — | |
| SCHEMBL7643714 | 0.84 | PDCD1 (0.32) | PDCD1CD274CHRNB2CHRNA4HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410665-B1 | POLYMERIZATION COORDINATION CATALYST FOR ALPHA-OLEFIN | BASELL POLYOLEFINE GMBH (DE) | 2002-06-25 | — | — | US | claimed |
| US-7442667-B2 | Preparation of supported cocatalysts | BOSELL POLYOLEFINE GMBH (DE) | 2008-10-28 | — | — | US | disclosed |
| US-20070149387-A1 | Preparation of supported cocatalysts | BASELL POLYOLEFINE GMBH (DE) | 2007-06-28 | — | — | US | disclosed |
| US-7202190-B1 | Supported catalyst system for the polymerization of olefins | TARGOR GMBH (DE) | 2007-04-10 | — | — | US | disclosed |
| EP-1697432-A2 | PREPARATION OF SUPPORTED COCATALYSTS | Basell Polyolefine GmbH (DE) | 2006-09-06 | — | — | EP | disclosed |
| US-20060154804-A1 | Preparation of dialkyl-ansa-metallocenes | BASELL POLYOLEFINE GMBH (DE) | 2006-07-13 | — | — | US | disclosed |
| US-6953829-B2 | Catalyst system and the use thereof | BASELL POLYOLEFINE GMBH (DE) | 2005-10-11 | — | — | US | disclosed |
| WO-2005063831-A2 | PREPARATION OF SUPPORTED COCATALYSTS | BASELL POLYOLEFINE GMBH (DE) | 2005-07-14 | — | — | WO | disclosed |
| EP-1461346-B1 | PREPARATION OF DIALKYL-ANSA-METALLOCENES | BASELL POLYOLEFINE GMBH (DE) | 2005-04-13 | — | — | EP | disclosed |
| EP-1461346-A1 | PREPARATION OF DIALKYL-ANSA-METALLOCENES | Basell Polyolefine GmbH (DE) | 2004-09-29 | — | — | EP | disclosed |
| US-20030109652-A1 | Catalyst system | BOHNEN HANS (DE) | 2003-06-12 | — | — | US | disclosed |
| US-6506856-B2 | Preparing polymers based on monomers having a C-C double and/or C-C triple bond by polymerization of these monomers in the presence of catalyst system comprising as active constituents a compound of an early transition metal | BASF AKTIENGESELLSCHAFT (DE) | 2003-01-14 | — | — | US | disclosed |
| US-20030008984-A1 | Novel catalyst system and the use thereof | BASELL POLYOLEFINE GMBH (DE) | 2003-01-09 | — | — | US | disclosed |
| US-6500908-B1 | ORGANOBORON-ALUMINUM COMPOUND, METALLOCENE, COCATALYTICALLY ACTIVE COMPOUND; BIS(DIMETHYLALUMINOXY)PENTAFLUOROPHENYLBORANE; OLEFIN POLYMERIZATION CATALYST | BASELL POLYOLEFINE GMBH (DE) | 2002-12-31 | — | — | US | disclosed |
| US-6482902-B1 | Catalyst system | TARGOR GMBH (DE) | 2002-11-19 | — | — | US | disclosed |
| US-6410665-B1 | POLYMERIZATION COORDINATION CATALYST FOR ALPHA-OLEFIN | BASELL POLYOLEFINE GMBH (DE) | 2002-06-25 | — | — | US | disclosed |
| US-6391989-B1 | COORDINATION CATALYST ON SUPPORT; POLYMERIZATION OF ALPHA-OLEFINS | BASELL POLYPROPYLEN GMBH (DE) | 2002-05-21 | — | — | US | disclosed |
| US-6271164-B1 | METALLOCENE CATALYST | LYONDELL CHEMICAL TECHNOLOGY, L.P. | 2001-08-07 | — | — | US | disclosed |
| US-6177526-B1 | METALLOCENE; COCATALYST; MODIFIED OXIDE CONTAINS ORGANIC SILICON RADICALS CONTAINING AT LEAST ONE OF THE GROUPS NITROGEN, FLUORINE, PHOSPHORUS OR SULFUR. | TARGOR GMBH (DE) | 2001-01-23 | — | — | US | disclosed |
| US-6177376-B1 | REACTING METALLOCENE WITH ORGANOLITHIUM COMPOUND AND GRIGNARD COMPOUND, ACTIVATION, CONTACTING WITH SUPPORT | TARGOR GMBH (DE) | 2001-01-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060154804-A1 | Preparation of dialkyl-ansa-metallocenes | C1R, SOD1, RPSA | PDCD1 2148/4885CD274 558/4885CHRNB2 2334/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.