Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 8/20 | 0.64 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.64 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.64 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.64 |
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.58 |
| ▸ | HSD17B3 | P37058 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | SHBG | P04278 | 2/20 | 0.58 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.58 |
| ▸ | G6PD | P11413 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11518397 | 1.00 | CYP19A1 (0.64) | CYP19A1AKR1B10AKR1B1OR51E2GPBAR1 | |
| SCHEMBL4585718 | 1.00 | CYP19A1 (0.64) | CYP19A1AKR1B10AKR1B1OR51E2GPBAR1 | |
| SCHEMBL11042029 | 0.86 | CYP19A1 (0.66) | CYP19A1AKR1B10AKR1B1OR51E2GPBAR1 | |
| SCHEMBL3988004 | 0.86 | CYP19A1 (0.66) | CYP19A1AKR1B10AKR1B1OR51E2GPBAR1 | |
| SCHEMBL8533582 | 0.85 | CYP19A1 (0.64) | CYP19A1AKR1B10AKR1B1OR51E2GPBAR1 | |
| SCHEMBL11804277 | 0.82 | SHBG (0.47) | CYP19A1AKR1B10AKR1B1OR51E2GPBAR1 | |
| SCHEMBL8836157 | 0.81 | ABL1 (0.61) | CYP19A1AKR1B10AKR1B1OR51E2GPBAR1 | |
| SCHEMBL4886360 | 0.81 | CYP19A1 (0.44) | CYP19A1AKR1B10AKR1B1OR51E2GPBAR1 | |
| SCHEMBL497634 | 0.81 | G6PD (0.61) | CYP19A1AKR1B10AKR1B1OR51E2GPBAR1 | |
| SCHEMBL4927255 | 0.80 | CYP19A1 (0.56) | CYP19A1AKR1B10AKR1B1OR51E2GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2999708-A2 | PROCESSES FOR THE PREPARATION OF DEHYDROEPIANDROSTERONE AND ITS INTERMEDIATES | Dr. Reddy's Laboratories Ltd. (IN) | 2016-03-30 | — | — | EP | disclosed |
| EP-1567645-A1 | INHIBITORS OF GST A3-3 AND GST A1-1 FOR THE TREATMENT OF CANCER | BIOVITRUM AB (SE) | 2005-08-31 | — | — | EP | disclosed |
| WO-2004048577-A1 | INHIBITORS OF GST A3-3 AND GST A1-1 FOR THE TREATMENT OF CANCER | BIOVITRUM AB (SE) | 2004-06-10 | — | — | WO | disclosed |
| US-5869090-A | ADMINISTERING THROUGH SKIN USING PHOSPHOLIPIDS AS VEHICLES | ROSENBAUM JERRY (US) | 1999-02-09 | — | — | US | disclosed |
| US-5709878-A | PHOSPHOLIPID | ROSENBAUM JERRY (US) | 1998-01-20 | — | — | US | disclosed |
| US-4110326-A | STEROIDS, CURARE-TYPE | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1978-08-29 | — | — | US | disclosed |