Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 7/20 | 0.51 |
| ▸ | PTPRB | P23467 | 1/20 | 0.49 |
| ▸ | CDC25A | P30304 | 1/20 | 0.49 |
| ▸ | CDC25B | P30305 | 1/20 | 0.49 |
| ▸ | PTEN | P60484 | 1/20 | 0.49 |
| ▸ | PTPMT1 | Q8WUK0 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3627230 | 0.92 | KEAP1 (0.60) | KEAP1FFAR1PTPRBCDC25ACDC25B | |
| SCHEMBL5762621 | 0.90 | KEAP1 (0.46) | KEAP1FFAR1PTPRBCDC25ACDC25B | |
| SCHEMBL592559 | 0.85 | FFAR1 (0.61) | KEAP1FFAR1ALDH1A1HDAC4MAOB | |
| SCHEMBL34463737 | 0.85 | FFAR1 (0.61) | KEAP1FFAR1ALDH1A1HDAC4MAOB | |
| (E)-3,4-Stilbendiol SCHEMBL27900284 | 0.82 | HSD17B10 (0.52) | KEAP1ALDH1A1HDAC4KDM4EPKM | |
| SCHEMBL2563669 | 0.80 | FFAR1 (0.64) | KEAP1FFAR1PTPRBCDC25ACDC25B | |
| SCHEMBL702077 | 0.80 | KEAP1 (0.43) | KEAP1FFAR1PTPRBCDC25ACDC25B | |
| SCHEMBL29237341 | 0.80 | GLA (0.54) | KEAP1FFAR1PTPRBCDC25ACDC25B | |
| SCHEMBL30967790 | 0.80 | GLA (0.54) | KEAP1FFAR1PTPRBCDC25ACDC25B | |
| SCHEMBL29237336 | 0.80 | GLA (0.54) | KEAP1FFAR1PTPRBCDC25ACDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1039834-B1 | OPTOACOUSTIC CONTRAST AGENTS AND METHODS FOR THEIR USE | IMARX PHARMACEUTICAL CORP (US) | 2005-09-28 | — | — | EP | claimed |