Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
| ▸ | PTPRB | P23467 | 1/20 | 0.48 |
| ▸ | CDC25A | P30304 | 1/20 | 0.48 |
| ▸ | CDC25B | P30305 | 1/20 | 0.48 |
| ▸ | PTEN | P60484 | 1/20 | 0.48 |
| ▸ | PTPMT1 | Q8WUK0 | 1/20 | 0.48 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.47 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | IAPP | P10997 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 5/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30967790 | 1.00 | GLA (0.54) | GLATDP1KEAP1PTPRBCDC25A | |
| SCHEMBL29237336 | 1.00 | GLA (0.54) | GLATDP1KEAP1PTPRBCDC25A | |
| SCHEMBL29237253 | 0.84 | CYP4F2 (0.56) | GLATDP1AKR1C3AKR1C2CYP4F2 | |
| SCHEMBL30217209 | 0.84 | CYP4F2 (0.56) | GLATDP1AKR1C3AKR1C2CYP4F2 | |
| SCHEMBL29237252 | 0.84 | CYP4F2 (0.56) | GLATDP1AKR1C3AKR1C2CYP4F2 | |
| SCHEMBL3627230 | 0.84 | KEAP1 (0.60) | KEAP1PTPRBCDC25ACDC25BPTEN | |
| SCHEMBL9633674 | 0.81 | KEAP1 (0.52) | KEAP1PTPRBCDC25ACDC25BPTEN | |
| SCHEMBL27455902 | 0.81 | AKR1C3 (0.58) | ALDH1A1KDM4EPKMSMN1; SMN2AKR1C3 | |
| SCHEMBL27832673 | 0.81 | GLA (0.56) | GLATDP1LTB4RLTB4R2ALDH1A1 | |
| SCHEMBL6254480 | 0.80 | KEAP1 (0.55) | KEAP1PTPRBCDC25ACDC25BPTEN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118201919-A | Indole compounds and methods of use | 健赞公司 | 2024-06-14 | — | — | CN | disclosed |