Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 8/20 | 0.40 |
| ▸ | NPC1 | O15118 | 6/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 6/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 6/20 | 0.40 |
| ▸ | RELA | Q04206 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | GLA | P06280 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | APP | P05067 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | STAT1 | P42224 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SNCA | P37840 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6255382 | 0.91 | SMN1; SMN2 (0.51) | SMN1; SMN2MAPTTP53RAB9ANPC1 | |
| SCHEMBL6254376 | 0.90 | SMN1; SMN2 (0.43) | SMN1; SMN2MAPTTP53RAB9ANPC1 | |
| SCHEMBL6254864 | 0.90 | RAB9A (0.48) | SMN1; SMN2MAPTTP53RAB9ANPC1 | |
| SCHEMBL6255933 | 0.81 | RAB9A (0.48) | SMN1; SMN2MAPTTP53RAB9ANPC1 | |
| SCHEMBL6258552 | 0.81 | KDM4E (0.51) | SMN1; SMN2MAPTTP53RAB9ANPC1 | |
| SCHEMBL6257841 | 0.80 | KDM4E (0.47) | SMN1; SMN2MAPTTP53RAB9ANPC1 | |
| SCHEMBL6252135 | 0.79 | SMN1; SMN2 (0.47) | SMN1; SMN2MAPTTP53RAB9ANPC1 | |
| SCHEMBL6253068 | 0.78 | KDM4E (0.43) | SMN1; SMN2MAPTTP53RAB9ANPC1 | |
| SCHEMBL6254362 | 0.78 | SMN1; SMN2 (0.49) | SMN1; SMN2MAPTTP53RAB9ANPC1 | |
| SCHEMBL6252091 | 0.77 | SMN1; SMN2 (0.48) | SMN1; SMN2MAPTTP53RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1143538-B1 | Organic electroluminescent element containing a silacyclopentadiene derivative | CHISSO CORP (JP) | 2005-09-14 | — | — | EP | disclosed |
| EP-0754691-B1 | Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative | CHISSO CORP (JP) | 2003-11-19 | — | — | EP | disclosed |
| EP-1143538-A1 | Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative | Chisso Corporation (JP) | 2001-10-10 | — | — | EP | disclosed |
| US-6051319-A | Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative | CHISSO CORPORATION (JP) | 2000-04-18 | — | — | US | disclosed |
| US-5986121-A | Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative | CHISSO CORPORATION (JP) | 1999-11-16 | — | — | US | disclosed |
| EP-0754691-A2 | Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative | CHISSO CORPORATION (JP) | 1997-01-22 | — | — | EP | disclosed |