Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.34 |
| ▸ | INPP5D | Q92835 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL394140 | 0.90 | MAPT (0.38) | NOS3ALDH1A1LMNAHTTMAPT | |
| SCHEMBL29605577 | 0.90 | MAPT (0.38) | NOS3ALDH1A1LMNAHTTMAPT | |
| SCHEMBL83801 | 0.83 | KDM4E (0.43) | NOS3ALDH1A1LMNAHTTMAPT | |
| SCHEMBL6602644 | 0.80 | NPSR1 (0.38) | NOS3ALDH1A1POLBMAPTRAB9A | |
| SCHEMBL82989 | 0.76 | TAAR1 (0.41) | NOS3ALDH1A1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL82712 | 0.76 | ALDH1A1 (0.43) | NOS3ALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL9393463 | 0.75 | TAAR1 (0.39) | ALDH1A1LMNAHTTMAPTSMN1; SMN2 | |
| SCHEMBL31323968 | 0.74 | ALDH1A1 (0.38) | NOS3ALDH1A1LMNAHTTPOLB | |
| SCHEMBL23178806 | 0.74 | ALDH1A1 (0.48) | NOS3ALDH1A1LMNAHTTMAPT | |
| SCHEMBL23179843 | 0.73 | TAAR1 (0.43) | NOS3ALDH1A1LMNAHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1305292-B1 | BIPHENYL CARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2012-06-20 | — | — | EP | disclosed |
| EP-1161420-B1 | FUNGICIDAL PYRAZOLE CARBOXANILIDES | BAYER CROPSCIENCE AG (DE) | 2005-05-11 | — | — | EP | disclosed |
| US-6821927-B1 | EXEMPLIFIED BY 2-(2-((6-(2-CHLOROPHENOXY)-5-FLUORO-4-PYRIMIDINYL)OXY) PHENYL)-N- HYDROXY-2-METHOXYIMINO)-N-METHYLACETAMIDE; PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2004-11-23 | — | — | US | disclosed |
| EP-1114038-B1 | ISOTHIAZOLE CARBOXYLIC ACID AMIDES | BAYER CROPSCIENCE AG (DE) | 2003-12-03 | — | — | EP | disclosed |