Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.50 |
| ▸ | ACACA | Q13085 | 1/20 | 0.50 |
| ▸ | ACLY | P53396 | 1/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 6/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 6/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 5/20 | 0.35 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6257317 | 1.00 | ACACB (0.50) | ACACBACACAACLYCYP4F2CYP4A11 | |
| SCHEMBL186369 | 0.93 | ACACB (0.44) | ACACBACACAACLYCYP4F2CYP4A11 | |
| SCHEMBL3279764 | 0.93 | ACACB (0.44) | ACACBACACAACLYCYP4F2CYP4A11 | |
| SCHEMBL187114 | 0.93 | ACACB (0.44) | ACACBACACAACLYCYP4F2CYP4A11 | |
| SCHEMBL185906 | 0.91 | ACACB (0.41) | ACACBACACAACLYCYP4F2CYP4A11 | |
| SCHEMBL186685 | 0.90 | ACACB (0.64) | ACACBACACAACLYCYP4F2CYP4A11 | |
| SCHEMBL186123 | 0.88 | ACACB (0.40) | ACACBACACAACLYCYP4F2CYP4A11 | |
| SCHEMBL186367 | 0.87 | ACACB (0.45) | ACACBACACAACLYCYP4F2CYP4A11 | |
| SCHEMBL7021398 | 0.83 | KMT2A (0.45) | CYP4F2CYP4A11PPARATSHRPPARG | |
| SCHEMBL19018787 | 0.80 | ELANE (0.41) | CYP4F2CYP4A11CHRM1CYP2C9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005068410-A1 | ETHER COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES | ESPERION THERAPEUTICS, INC. (US) | 2005-07-28 | — | — | WO | disclosed |
| US-20040192771-A1 | Ether compounds and compositions for cholesterol management and related uses | ESPERION THERAPEUTICS, INC. | 2004-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040192771-A1 | Ether compounds and compositions for cholesterol management and related uses | GPR119, PNLIP, NR1H2 | ACACB 173/4885ACACA 118/4885ACLY 706/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.