Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | WDR5 | P61964 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6256136 | 0.83 | MAPT (0.51) | TSHRCYP1A2ALDH1A1MAPT | |
| SCHEMBL6253735 | 0.83 | TSHR (0.41) | CYP2A6TSHRCYP1A2HSD11B1ALDH1A1 | |
| SCHEMBL6253454 | 0.80 | TSHR (0.43) | CYP2A6TSHRCYP1A2HSD11B1ALDH1A1 | |
| SCHEMBL6254591 | 0.79 | ALDH1A1 (0.39) | TSHRALDH1A1MAPT | |
| SCHEMBL6252323 | 0.76 | CYP1A2 (0.40) | CYP2A6TSHRCYP1A2HSD11B1ALDH1A1 | |
| SCHEMBL6255419 | 0.76 | PDE4B (0.31) | ALDH1A1 | |
| SCHEMBL6267869 | 0.75 | CYP2A6 (0.39) | CYP2A6TSHRCYP1A2HSD11B1ALDH1A1 | |
| SCHEMBL6255991 | 0.75 | KDM4E (0.45) | CYP2A6TSHRCYP1A2ALDH1A1MAPT | |
| SCHEMBL6256562 | 0.75 | PLA2G10 (0.32) | CYP1A2 | |
| SCHEMBL6257082 | 0.74 | HSD17B1 (0.37) | CYP2A6TSHRCYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1143538-B1 | Organic electroluminescent element containing a silacyclopentadiene derivative | CHISSO CORP (JP) | 2005-09-14 | — | — | EP | disclosed |
| EP-0754691-B1 | Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative | CHISSO CORP (JP) | 2003-11-19 | — | — | EP | disclosed |
| EP-1143538-A1 | Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative | Chisso Corporation (JP) | 2001-10-10 | — | — | EP | disclosed |
| US-6051319-A | Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative | CHISSO CORPORATION (JP) | 2000-04-18 | — | — | US | disclosed |
| US-5986121-A | Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative | CHISSO CORPORATION (JP) | 1999-11-16 | — | — | US | disclosed |
| EP-0754691-A2 | Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative | CHISSO CORPORATION (JP) | 1997-01-22 | — | — | EP | disclosed |