Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 12/20 | 0.53 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.37 |
| ▸ | ACP1 | P24666 | 2/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 2/20 | 0.36 |
| ▸ | PI4KA | P42356 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL625601 | 0.88 | FYN (0.53) | FYNMKNK1ACP1ACHEGSK3B | |
| SCHEMBL625476 | 0.85 | FYN (0.73) | FYNMKNK1 | |
| SCHEMBL626614 | 0.85 | FYN (0.57) | FYNMKNK1 | |
| SCHEMBL624884 | 0.84 | FYN (0.51) | FYN | |
| SCHEMBL625477 | 0.82 | FYN (0.50) | FYNACP1 | |
| SCHEMBL625602 | 0.74 | FYN (0.39) | FYNGSK3BPI4KA | |
| SCHEMBL1945181 | 0.73 | FYN (0.87) | FYNMKNK1 | |
| SCHEMBL626615 | 0.73 | FYN (0.57) | FYNMKNK1 | |
| SCHEMBL624885 | 0.73 | FYN (0.51) | FYN | |
| SCHEMBL624430 | 0.72 | FYN (0.72) | FYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020215-A1 | AMINO- IMIDAZOLOTHIADIAZOLES FOR USE AS PROTEIN OR LIPID KINASE INHIBITORS | CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) (ES) | 2012-02-16 | — | — | WO | disclosed |