Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 6/20 | 0.50 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | F2RL3 | Q96RI0 | 4/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 7/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | ACP1 | P24666 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1945185 | 0.89 | FYN (0.58) | FYNF2RL3CA12CA1CA2 | |
| SCHEMBL624431 | 0.87 | FYN (0.48) | FYNPIK3R1PIK3CAF2RL3CA12 | |
| SCHEMBL1947142 | 0.85 | FYN (0.68) | FYNF2RL3 | |
| SCHEMBL624392 | 0.85 | FYN (0.54) | FYNF2RL3 | |
| SCHEMBL625476 | 0.83 | FYN (0.73) | FYNPIK3CA | |
| SCHEMBL625601 | 0.82 | FYN (0.53) | FYNACP1 | |
| SCHEMBL625600 | 0.82 | FYN (0.53) | FYNACP1 | |
| SCHEMBL624837 | 0.80 | PIM1 (0.47) | F2RL3 | |
| SCHEMBL625027 | 0.78 | CA12 (0.42) | FYNPIK3CAF2RL3CA12CA1 | |
| SCHEMBL626460 | 0.77 | MAPT (0.46) | FYNF2RL3MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020215-A1 | AMINO- IMIDAZOLOTHIADIAZOLES FOR USE AS PROTEIN OR LIPID KINASE INHIBITORS | CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) (ES) | 2012-02-16 | — | — | WO | disclosed |