Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 9/20 | 0.55 |
| ▸ | PIM1 | P11309 | 11/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL623872 | 0.88 | FYN (0.52) | FYNPIM1KCNH2 | |
| SCHEMBL1944058 | 0.86 | FYN (0.72) | FYNPIM1KCNH2 | |
| SCHEMBL626258 | 0.84 | PIM1 (0.68) | FYNPIM1KCNH2 | |
| SCHEMBL1945309 | 0.84 | FYN (0.71) | FYNPIM1KCNH2 | |
| SCHEMBL623434 | 0.84 | FYN (0.57) | FYNPIM1KCNH2 | |
| SCHEMBL625501 | 0.83 | PIM1 (0.43) | PIM1KCNH2 | |
| SCHEMBL625291 | 0.83 | PIM1 (0.68) | FYNPIM1KCNH2 | |
| Hydrochloric Acid SCHEMBL625022 | 0.83 | FYN (0.58) | FYNPIM1KCNH2 | |
| SCHEMBL624016 | 0.82 | PIM1 (0.49) | PIM1KCNH2 | |
| SCHEMBL625495 | 0.81 | PIM1 (0.46) | FYNPIM1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020217-A1 | AMINO- IMIDAZOLOTHIADIAZOLES FOR USE AS PROTEIN OR LIPID KINASE INHIBITORS | CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) (ES) | 2012-02-16 | — | — | WO | disclosed |