Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 12/20 | 0.68 |
| ▸ | FYN | P06241 | 7/20 | 0.59 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.57 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1944058 | 0.91 | FYN (0.72) | PIM1FYNKCNH2 | |
| SCHEMBL1945309 | 0.90 | FYN (0.71) | PIM1FYNKCNH2 | |
| Hydrochloric Acid SCHEMBL625022 | 0.89 | FYN (0.58) | PIM1FYNKCNH2 | |
| SCHEMBL625291 | 0.89 | PIM1 (0.68) | PIM1FYNKCNH2 | |
| SCHEMBL623434 | 0.88 | FYN (0.57) | PIM1FYNHASPINKCNH2PIM2 | |
| SCHEMBL625500 | 0.84 | FYN (0.55) | PIM1FYNKCNH2 | |
| SCHEMBL623872 | 0.82 | FYN (0.52) | PIM1FYNKCNH2 | |
| SCHEMBL625560 | 0.82 | FYN (0.50) | PIM1FYNKCNH2PIM2 | |
| SCHEMBL102682 | 0.81 | PIM1 (1.00) | PIM1KCNH2 | |
| SCHEMBL16211078 | 0.81 | PIM1 (1.00) | PIM1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020217-A1 | AMINO- IMIDAZOLOTHIADIAZOLES FOR USE AS PROTEIN OR LIPID KINASE INHIBITORS | CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) (ES) | 2012-02-16 | — | — | WO | disclosed |