Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | TTR | P02766 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10804895 | 0.96 | ALDH1A1 (0.60) | ALDH1A1MAPTLMNAMAPK1NPC1 | |
| SCHEMBL7907585 | 0.92 | NPC1 (0.59) | ALDH1A1MAPTLMNAMAPK1NPC1 | |
| SCHEMBL2002273 | 0.87 | MAPT (0.55) | ALDH1A1MAPTLMNAMAPK1NPC1 | |
| SCHEMBL11221739 | 0.87 | MAPT (0.56) | ALDH1A1MAPTLMNAMAPK1NPC1 | |
| SCHEMBL8973132 | 0.86 | CYP19A1 (0.57) | ALDH1A1MAPTLMNANPC1RAB9A | |
| SCHEMBL9638940 | 0.85 | ALDH1A1 (0.56) | ALDH1A1MAPTLMNAMAPK1NPC1 | |
| SCHEMBL8973683 | 0.84 | ALDH1A1 (0.56) | ALDH1A1MAPTLMNAMAPK1NPC1 | |
| SCHEMBL6431028 | 0.84 | MAPT (0.59) | ALDH1A1MAPTLMNAMAPK1NPC1 | |
| SCHEMBL442509 | 0.83 | MAPT (0.48) | ALDH1A1MAPTLMNAMAPK1NPC1 | |
| SCHEMBL12312148 | 0.83 | ALDH1A1 (0.64) | ALDH1A1MAPTLMNAMAPK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1166749-B1 | Composition and process for dyeing keratinic fibres | WELLA AG (DE) | 2005-10-12 | — | — | EP | disclosed |
| EP-1166749-A2 | Composition and process for dyeing keratinic fibres | Wella Aktiengesellschaft (DE) | 2002-01-02 | — | — | EP | disclosed |
| EP-0328968-B1 | PROCESS FOR THE PREPARATION OF 4-ACYLAMINO-2-AMINO ALKOXY BENZENES | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-05-12 | — | — | EP | disclosed |
| EP-0292985-B1 | PROCESS FOR PREPARING 2,4-DINITRO-PHENYLETHERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-03-25 | — | — | EP | disclosed |
| US-5047586-A | Process for the preparation of 4-acylamino-2-aminoalkoxybenzenes | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-09-10 | — | — | US | disclosed |
| EP-0328968-A2 | Process for the preparation of 4-acylamino-2-amino alkoxy benzenes | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-08-23 | — | — | EP | disclosed |
| US-4847426-A | Process for the preparation of 2,4-dinitrophenyl ethers | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-07-11 | — | — | US | disclosed |
| EP-0292985-A1 | Process for preparing 2,4-dinitro-phenylethers | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-11-30 | — | — | EP | disclosed |
| EP-0124084-B1 | PROCESS FOR THE PREPARATION OF 6-CHLORO-2,4-DINITROPHENOL | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-09-07 | — | — | EP | disclosed |
| US-4695656-A | Process for the preparation of 2,4-dinitrophenyl ethers | CASSELLA AKTIENGESELLSCHAFT (DE) | 1987-09-22 | — | — | US | disclosed |
| US-4686301-A | Process for the preparation of 2,4-dinitrophenol alkoxyalkyl ethers | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-08-11 | — | — | US | disclosed |
| EP-0204229-A1 | Process for preparing 2,4-dinitrophenol-alkoxyalkyl ethers | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-12-10 | — | — | EP | disclosed |
| EP-0204111-A2 | Process for the preparation of 2,4-dinitrophenyl ethers | CASSELLA Aktiengesellschaft (DE) | 1986-12-10 | — | — | EP | disclosed |
| EP-0200955-A2 | Process for the preparation of 2,4-dinitrophenyl ethers | CASSELLA Aktiengesellschaft (DE) | 1986-11-12 | — | — | EP | disclosed |
| US-4540832-A | Process for the preparation of 6-chloro-2,4-dinitrophenol | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-09-10 | — | — | US | disclosed |
| EP-0124084-A2 | Process for the preparation of 6-chloro-2,4-dinitrophenol | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-11-07 | — | — | EP | disclosed |
| EP-0007738-B1 | PROCESS FOR PRODUCING 2-AMINO-4-ACYLAMINOPHENYL ETHER AND 2,4-DIAMINOPHENYL ETHER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-12-29 | — | — | EP | disclosed |
| EP-0007738-A1 | Process for producing 2-amino-4-acylaminophenyl ether and 2,4-diaminophenyl ether | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1980-02-06 | — | — | EP | disclosed |