Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | HSPB1 | P04792 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.52 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11221739 | 0.95 | MAPT (0.56) | NPC1RECQLRAB9AMAPTMEN1 | |
| SCHEMBL6255209 | 0.92 | ALDH1A1 (0.53) | NPC1RECQLRAB9AMAPTMEN1 | |
| SCHEMBL4101417 | 0.90 | TSHR (0.59) | NPC1RECQLRAB9AMAPTMEN1 | |
| SCHEMBL6575773 | 0.90 | MEN1 (0.56) | NPC1RECQLRAB9AMAPTMEN1 | |
| SCHEMBL29695817 | 0.90 | TSHR (0.59) | NPC1RECQLRAB9AMAPTMEN1 | |
| SCHEMBL8973132 | 0.90 | CYP19A1 (0.57) | NPC1RECQLRAB9AMAPTMEN1 | |
| SCHEMBL9638940 | 0.89 | ALDH1A1 (0.56) | NPC1RECQLRAB9AMAPTMEN1 | |
| SCHEMBL10801307 | 0.89 | NPC1 (0.57) | NPC1RECQLRAB9AMAPTMEN1 | |
| SCHEMBL8973683 | 0.89 | ALDH1A1 (0.56) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL6651358 | 0.89 | PRSS1 (0.54) | NPC1RECQLRAB9AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6198007-B1 | REACTING 1-HALOGENO-2,4-DINITROBENZENES WITH MONO-ALKALI METAL SALTS OF SPECIFIC DIOLS | BAYER AKTIENGESELLSCHAFT (DE) | 2001-03-06 | — | — | US | disclosed |
| EP-1046632-A1 | Process for the preparation of 1-substituted 2,4-dinitrobenzenes | Bayer Aktiengesellschaft (DE) | 2000-10-25 | — | — | EP | disclosed |
| EP-0573041-B1 | Nonlinear optical material, method of manufacturing the same, and wavelength converter | MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) | 1997-01-08 | — | — | EP | disclosed |
| EP-0573041-A1 | Nonlinear optical material, method of manufacturing the same, and wavelength converter | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1993-12-08 | — | — | EP | disclosed |