SCHEMBL6255348

SCHEMBL6255348

CC(C)(C)C1=CC(Cc2ccccc2)=CC1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CALM1 P0DP23 1/20 0.38
HPGD P15428 2/20 0.37
TSHR P16473 1/20 0.37
LMNA P02545 2/20 0.36
CYP2D6 P10635 1/20 0.36
TAAR1 Q96RJ0 2/20 0.34
SLC6A2 P23975 1/20 0.34
HRH3 Q9Y5N1 1/20 0.33
HTR1D P28221 1/20 0.33
HTR1B P28222 1/20 0.33
MAPT P10636 2/20 0.33
USP2 O75604 1/20 0.33
ALDH1A1 P00352 1/20 0.33
ALOX15 P16050 1/20 0.33
RECQL P46063 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
HSD17B10 Q99714 1/20 0.33
LTA4H P09960 2/20 0.32
KDM4E B2RXH2 1/20 0.31
CYP3A4 P08684 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12815028 0.85 CYP2B6 (0.35) CALM1HPGDTSHRLMNACYP2D6
SCHEMBL16458422 0.82 CALM1 (0.32) CALM1LMNACYP2D6TAAR1SLC6A2
SCHEMBL12814710 0.81 CALM1 (0.37) CALM1HPGDTSHRHRH3MAPT
SCHEMBL16458745 0.78 IDH1 (0.33) CALM1LMNACYP2D6HTR1DHTR1B
SCHEMBL6251956 0.76 CALM1 (0.42) CALM1LMNATAAR1HRH3MAPT
SCHEMBL12814840 0.76 KIF11 (0.38) CYP2D6HRH3ALDH1A1NPSR1KDM4E
SCHEMBL12815462 0.75 KIF11 (0.39) CYP2D6CYP3A4SIGMAR1
Hydrochloric Acid SCHEMBL12827458 0.74 CALM1 (0.41) CALM1TSHRLMNACYP2D6TAAR1
SCHEMBL1028776 0.73 CALM1 (0.44) CALM1TSHRLMNACYP2D6TAAR1
SCHEMBL6250272 0.73 TP53 (0.41) CALM1LMNATAAR1HRH3MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0926150-B1 Production of alkali metal cyclopentadienylides and production of dihalobis(eta-substituted-cyclopentadienyl) zirconium from alkali metal cyclopentadienylides HONSHU CHEMICAL IND (JP) 2005-09-07 EP disclosed
US-6046346-A Production of alkali metal cyclopentadienylide and production of dihalobis (η-substituted-cyclopentadienyl) zirconium from alkali metal cyclopentadienylide HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2000-04-04 US disclosed
EP-0926150-A2 Production of alkali metal cyclopentadienylide and production of dihalobis(eta-substituted-cyclopentadienyl) zirconium from alkali metal cyclopentadienylide Honshu Chemical Industry Co. Ltd. (JP) 1999-06-30 EP disclosed