Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.37 |
| ▸ | FABP4 | P15090 | 7/20 | 0.37 |
| ▸ | FABP5 | Q01469 | 6/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.35 |
| ▸ | C5 | P01031 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5374067 | 0.85 | LTB4R2 (0.42) | TAS2R14MEN1KMT2AFABP4FABP5 | |
| SCHEMBL5358344 | 0.79 | PPARD (0.40) | TAS2R14ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL6256866 | 0.75 | NPC1 (0.39) | POLBMMP2C5MMP3 | |
| SCHEMBL5360875 | 0.74 | PTPN11 (0.44) | ALDH1A1MEN1KMT2APTPN11 | |
| SCHEMBL5374060 | 0.72 | LTB4R2 (0.49) | — | |
| SCHEMBL2698411 | 0.71 | POLB (0.69) | POLBALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL2698951 | 0.71 | POLB (0.69) | POLBALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL6255353 | 0.71 | LTB4R2 (0.45) | MEN1KMT2A | |
| SCHEMBL5365598 | 0.69 | PTPN11 (0.41) | ALDH1A1MEN1KMT2APTPN11 | |
| SCHEMBL6254035 | 0.69 | POLB (0.41) | POLBALDH1A1MMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572629-A1 | COMPOUNDS WHICH MODULATE PPARϝ TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | Galderma Research & Development, S.N.C. (FR) | 2005-09-14 | — | — | EP | claimed |
| WO-2004052840-A1 | COMPOUNDS WHICH MODULATE PPARϜ TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-06-24 | — | — | WO | claimed |