Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCZ | Q05513 | 1/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 13/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 11/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | CCNC | P24863 | 2/20 | 0.33 |
| ▸ | CDK8 | P49336 | 2/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6254591 | 0.83 | ALDH1A1 (0.39) | SLC22A12CYP2C9CYP2C19 | |
| SCHEMBL6257256 | 0.82 | PRKCZ (0.46) | PRKCZCYP11B2CYP11B1CYP1A2CYP3A4 | |
| SCHEMBL6256199 | 0.80 | PRKCZ (0.47) | PRKCZSLC22A12CYP11B2CYP11B1CYP1A2 | |
| SCHEMBL8167292 | 0.77 | ALDH1A1 (0.38) | SLC22A12CYP2C9CYP2C19 | |
| SCHEMBL6254194 | 0.77 | PRKCZ (0.44) | PRKCZSLC22A12CYP11B2CYP11B1CYP1A2 | |
| SCHEMBL6259245 | 0.77 | PRKCZ (0.44) | PRKCZSLC22A12CYP11B2CYP11B1CYP1A2 | |
| SCHEMBL6257000 | 0.76 | CYP11B1 (0.36) | SLC22A12CYP11B2CYP11B1CYP2C9CYP2C19 | |
| SCHEMBL6252332 | 0.76 | PRKCZ (0.43) | PRKCZSLC22A12CYP11B2CYP11B1CYP1A2 | |
| SCHEMBL6258897 | 0.75 | KDM4E (0.38) | CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL6255419 | 0.75 | PDE4B (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1143538-B1 | Organic electroluminescent element containing a silacyclopentadiene derivative | CHISSO CORP (JP) | 2005-09-14 | — | — | EP | disclosed |
| EP-0754691-B1 | Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative | CHISSO CORP (JP) | 2003-11-19 | — | — | EP | disclosed |
| EP-1143538-A1 | Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative | Chisso Corporation (JP) | 2001-10-10 | — | — | EP | disclosed |
| US-6051319-A | Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative | CHISSO CORPORATION (JP) | 2000-04-18 | — | — | US | disclosed |
| US-5986121-A | Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative | CHISSO CORPORATION (JP) | 1999-11-16 | — | — | US | disclosed |
| EP-0754691-A2 | Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative | CHISSO CORPORATION (JP) | 1997-01-22 | — | — | EP | disclosed |