Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 4/20 | 0.32 |
| ▸ | RECQL | P46063 | 3/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29803962 | 0.77 | TSHR (0.33) | TDP1ALDH1A1TSHRRECQLCES2 | |
| SCHEMBL8901551 | 0.72 | TDP1 (0.38) | TDP1ALDH1A1TSHRRECQLCES2 | |
| SCHEMBL27719653 | 0.72 | TDP1 (0.38) | TDP1ALDH1A1TSHRRECQLCES2 | |
| SCHEMBL10395696 | 0.72 | TDP1 (0.38) | TDP1ALDH1A1TSHRRECQLCES2 | |
| SCHEMBL4939588 | 0.69 | ALDH1A1 (0.36) | TDP1ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL11579829 | 0.69 | CYP3A4 (0.30) | TSHR | |
| SCHEMBL28456357 | 0.68 | TSHR (0.35) | TDP1ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL28783597 | 0.68 | ALDH1A1 (0.35) | TDP1ALDH1A1TSHRRECQLCES2 | |
| SCHEMBL11883317 | 0.68 | TDP1 (0.32) | TDP1ALDH1A1TSHRRECQLMEN1 | |
| SCHEMBL11434125 | 0.68 | ALDH1A1 (0.40) | TDP1ALDH1A1TSHRRECQLGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005053768-A1 | BIOACTIVE ORGANIC COATINGS WHICH CAN BE APPLIED TO VASCULAR ENDOPROSTHESES | ALCHIMER (FR) | 2005-06-16 | — | — | WO | disclosed |