SCHEMBL8901551

SCHEMBL8901551

CCCCCCCCCCCCCCCCCCCCCCOC1(C)CO1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.38
ALDH1A1 P00352 1/20 0.38
CES2 O00748 1/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
RECQL P46063 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
TSHR P16473 4/20 0.35
THRB P10828 2/20 0.35
HTT P42858 1/20 0.34
MAPT P10636 1/20 0.34
LPAR1 Q92633 2/20 0.33
LPAR3 Q9UBY5 2/20 0.33
LPAR2 Q9HBW0 1/20 0.33
DNM1 Q05193 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10395696 1.00 TDP1 (0.38) TDP1ALDH1A1CES2MEN1KMT2A
SCHEMBL11507214 0.91
SCHEMBL6256137 0.72 TDP1 (0.34) TDP1ALDH1A1CES2MEN1KMT2A
SCHEMBL9177155 0.71 ALDH1A1 (0.44) TDP1ALDH1A1CES2MEN1KMT2A
SCHEMBL11327251 0.71 ALDH1A1 (0.44) TDP1ALDH1A1CES2MEN1KMT2A
SCHEMBL2623198 0.71 ALDH1A1 (0.44) TDP1ALDH1A1CES2MEN1KMT2A
SCHEMBL5072636 0.71 ALDH1A1 (0.44) TDP1ALDH1A1CES2MEN1KMT2A
SCHEMBL11337952 0.71 ALDH1A1 (0.44) TDP1ALDH1A1CES2MEN1KMT2A
SCHEMBL8458691 0.71 ALDH1A1 (0.44) TDP1ALDH1A1CES2MEN1KMT2A
SCHEMBL4939588 0.71 ALDH1A1 (0.36) TDP1ALDH1A1MEN1KMT2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1997031950-A1 CARBOXYMETHYL CELLULOSE ETHERS HAVING, AS SUBSTITUENTS, LONG CHAIN GROUPS LAMBERTI S.P.A. (IT) 1997-09-04 WO disclosed