SCHEMBL6256196

SCHEMBL6256196

Cc1cc(N2CCCCCC(O)C2C)ccc1N

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAD52 P43351 3/20 0.40
GAA P10253 2/20 0.40
THRB P10828 1/20 0.38
MAPT P10636 3/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
S100B P04271 2/20 0.36
ALDH1A1 P00352 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
MEN1 O00255 1/20 0.36
LMNA P02545 1/20 0.36
PKM P14618 1/20 0.36
ALOX15 P16050 1/20 0.36
MAPK1 P28482 1/20 0.36
HTT P42858 1/20 0.36
KMT2A Q03164 1/20 0.36
KDM4E B2RXH2 2/20 0.35
GFER P55789 2/20 0.35
NR1I2 O75469 2/20 0.34
SMARCA2 P51531 2/20 0.34
SMARCA4 P51532 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6290240 0.84 GAA (0.43) RAD52GAATHRBMAPTL3MBTL1
SCHEMBL15148613 0.78 RAD52 (0.45) RAD52GAATHRBMAPTALDH1A1
SCHEMBL6697927 0.76 RAD52 (0.41) RAD52GAATHRBMAPTL3MBTL1
SCHEMBL27695209 0.75 RAD52 (0.43) RAD52GAATHRBMAPTL3MBTL1
SCHEMBL6254855 0.74 GAA (0.52) RAD52GAATHRBMAPTL3MBTL1
SCHEMBL6223226 0.74 GAA (0.43) RAD52GAATHRBMAPTL3MBTL1
SCHEMBL6267908 0.73 GAA (0.48) RAD52GAATHRBMAPTL3MBTL1
SCHEMBL6256943 0.73 GAA (0.51) RAD52GAATHRBMAPTL3MBTL1
SCHEMBL6220205 0.73 GAA (0.58) RAD52GAATHRBMAPTL3MBTL1
SCHEMBL6505403 0.72 GAA (0.43) RAD52GAATHRBMAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005068431-A1 COMPOSITION FOR DYEING KERATIN FIBRES, COMPRISING AT LEAST ONE PARA-PHENYLENEDIAMINE DERIVATIVE L'OREAL (FR) 2005-07-28 WO claimed