Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.43 |
| ▸ | RAD52 | P43351 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 7/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | THRB | P10828 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6494087 | 0.83 | MAPT (0.47) | GAARAD52MAPTKDM4ETHRB | |
| SCHEMBL15148613 | 0.81 | RAD52 (0.45) | GAARAD52MAPTKDM4ETHRB | |
| SCHEMBL6697927 | 0.77 | RAD52 (0.41) | GAARAD52MAPTKDM4ETHRB | |
| SCHEMBL6290240 | 0.76 | GAA (0.43) | GAARAD52MAPTKDM4ETHRB | |
| SCHEMBL13638851 | 0.74 | ADORA2A (0.45) | GAARAD52FFAR1 | |
| SCHEMBL2926286 | 0.73 | RAD52 (0.42) | GAARAD52MAPTKDM4ETHRB | |
| SCHEMBL6256196 | 0.72 | RAD52 (0.40) | GAARAD52MAPTKDM4ETHRB | |
| SCHEMBL4297198 | 0.72 | HRH3 (0.63) | GAARAD52MAPTKDM4EHRH3 | |
| SCHEMBL27695209 | 0.72 | RAD52 (0.43) | GAARAD52MAPTKDM4ETHRB | |
| SCHEMBL2885437 | 0.72 | HRH3 (0.63) | GAARAD52MAPTKDM4EHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6923835-B2 | Bis-para-phenylenediamine derivatives comprising a pyrrolidyl group and use of these derivatives for dyeing keratin fibres | L'OREAL S.A. (FR) | 2005-08-02 | — | — | US | disclosed |