Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 4/20 | 0.36 |
| ▸ | SMARCA2 | P51531 | 4/20 | 0.36 |
| ▸ | SMARCA4 | P51532 | 4/20 | 0.36 |
| ▸ | PBRM1 | Q86U86 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | LGMN | Q99538 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.30 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15148613 | 0.79 | RAD52 (0.45) | RAD52GAAARTHRBNR1I2 | |
| SCHEMBL6505403 | 0.77 | GAA (0.43) | RAD52GAATHRBMAPTKDM4E | |
| SCHEMBL6256196 | 0.76 | RAD52 (0.40) | RAD52GAAARTHRBNR1I2 | |
| SCHEMBL6290240 | 0.74 | GAA (0.43) | RAD52GAAARTHRBNR1I2 | |
| SCHEMBL13638851 | 0.72 | ADORA2A (0.45) | RAD52GAAFFAR1 | |
| SCHEMBL6385420 | 0.72 | GAA (0.44) | RAD52GAAARTHRBMAPT | |
| SCHEMBL6254071 | 0.72 | GAA (0.55) | RAD52GAATHRBSMARCA2SMARCA4 | |
| SCHEMBL2926286 | 0.71 | RAD52 (0.42) | RAD52GAATHRBNR1I2SMARCA2 | |
| SCHEMBL27695209 | 0.70 | RAD52 (0.43) | RAD52GAATHRBMAPTKDM4E | |
| SCHEMBL6505168 | 0.70 | RAD52 (0.41) | RAD52GAATHRBNR1I2SMARCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040064902-A1 | Oxidatiton dyeing composition based on 1-(4-aminophenyl) pyrrolidines substituted in position 2 and 5 | L'OREAL S.A. (FR) | 2004-04-08 | — | — | US | claimed |
| EP-1341507-A1 | OXIDATION DYEING COMPOSITION BASED ON 1-(4-AMINOPHENYL) PYRROLIDINES SUBSTITUTED IN POSITIONS 2 AND 5 | L'OREAL (FR) | 2003-09-10 | — | — | EP | claimed |
| WO-2002045668-A1 | OXIDATION DYEING COMPOSITION BASED ON 1-(4-AMINOPHENYL) PYRROLIDINES SUBSTITUTED IN POSITIONS 2 AND 5 | L'OREAL (FR) | 2002-06-13 | — | — | WO | claimed |
| US-20040064902-A1 | Oxidatiton dyeing composition based on 1-(4-aminophenyl) pyrrolidines substituted in position 2 and 5 | L'OREAL S.A. (FR) | 2004-04-08 | — | — | US | disclosed |
| EP-1341507-A1 | OXIDATION DYEING COMPOSITION BASED ON 1-(4-AMINOPHENYL) PYRROLIDINES SUBSTITUTED IN POSITIONS 2 AND 5 | L'OREAL (FR) | 2003-09-10 | — | — | EP | disclosed |
| WO-2002045668-A1 | OXIDATION DYEING COMPOSITION BASED ON 1-(4-AMINOPHENYL) PYRROLIDINES SUBSTITUTED IN POSITIONS 2 AND 5 | L'OREAL (FR) | 2002-06-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040064902-A1 | Oxidatiton dyeing composition based on 1-(4-aminophenyl) pyrrolidines substituted in position 2 and 5 | COX5B, KRT18, PYCR1 | RAD52 631/4885GAA 4466/4885AR 566/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.