SCHEMBL6256434

SCHEMBL6256434

O=C(NCCCO)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.49
CA2 P00918 7/20 0.47
CA1 P00915 6/20 0.47
POLB P06746 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
STS P08842 1/20 0.44
THRB P10828 1/20 0.42
CA3 P07451 2/20 0.40
CA5A P35218 2/20 0.40
CA5B Q9Y2D0 2/20 0.40
CA12 O43570 1/20 0.40
CA4 P22748 1/20 0.40
CA6 P23280 1/20 0.40
CA7 P43166 1/20 0.40
CA9 Q16790 1/20 0.40
CA14 Q9ULX7 1/20 0.40
EPHX1 P07099 1/20 0.38
L3MBTL1 Q9Y468 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6260219 0.93 MEN1 (0.50) ALDH1A1CA2CA1POLBSMN1; SMN2
SCHEMBL28026596 0.89 ALDH1A1 (0.60) ALDH1A1CA2CA1POLBSMN1; SMN2
SCHEMBL6256496 0.86 CA2 (0.51) ALDH1A1CA2CA1POLBSMN1; SMN2
SCHEMBL6260502 0.84 ALDH1A1 (0.42) ALDH1A1CA2CA1POLBSMN1; SMN2
SCHEMBL4561705 0.84 CA2 (0.49) ALDH1A1CA2CA1POLBSMN1; SMN2
SCHEMBL28319052 0.83 CA1 (0.43) ALDH1A1CA2CA1POLBSMN1; SMN2
SCHEMBL28320112 0.83 CA1 (0.43) ALDH1A1CA2CA1POLBSMN1; SMN2
SCHEMBL11021321 0.82 CA2 (0.45) ALDH1A1CA2CA1POLBSMN1; SMN2
SCHEMBL6260269 0.82 CA2 (0.45) ALDH1A1CA2CA1POLBSMN1; SMN2
SCHEMBL8144274 0.82 CA2 (0.45) ALDH1A1CA2CA1POLBSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005063842-A1 (POLY-)URETDIONES COMPRISING CHEMICALLY COUPLED PERFLUOROALKYL COMPOUNDS, AND METHOD FOR THE PRODUCTION THEREOF INSTITUT FÜR POLYMERFORSCHUNG DRESDEN E.V. (DE) 2005-07-14 WO disclosed