Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.51 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.46 |
| ▸ | SLC6A9 | P48067 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6829910 | 0.87 | MEN1 (0.50) | LTA4HAOC3SLC6A9ALDH1A1CYP2D6 | |
| SCHEMBL6830431 | 0.87 | UTS2R (0.42) | SLC6A9KMT2A | |
| SCHEMBL6831540 | 0.83 | MEN1 (0.42) | LTA4HAOC3SLC6A9ALDH1A1CYP2D6 | |
| SCHEMBL6831514 | 0.83 | AOC3 (0.49) | LTA4HAOC3SLC6A9ALDH1A1MAPT | |
| SCHEMBL641514 | 0.81 | FOLH1 (0.46) | AOC3SLC6A4SLC6A3TBXA2RFOLH1 | |
| SCHEMBL21358345 | 0.81 | FOLH1 (0.46) | AOC3SLC6A4SLC6A3TBXA2RFOLH1 | |
| SCHEMBL6512170 | 0.79 | TBXA2R (0.50) | AOC3TBXA2RFOLH1 | |
| SCHEMBL27868603 | 0.79 | TBXA2R (0.50) | AOC3TBXA2RFOLH1 | |
| SCHEMBL2743522 | 0.79 | TBXA2R (0.50) | AOC3TBXA2RFOLH1 | |
| SCHEMBL6271310 | 0.78 | SLC6A9 (0.49) | LTA4HSLC6A9ALDH1A1CYP2D6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005063707-A1 | ENANTIOSPECIFIC PROCESS FOR THE PREPARATION OF PAROXETINE INTERMEDIATE | NATCO PHARMA LIMITED (IN) | 2005-07-14 | — | — | WO | disclosed |