Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | SLC6A9 | P48067 | 4/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6831540 | 0.88 | MEN1 (0.42) | MEN1KMT2AAOC3LTA4HALDH1A1 | |
| SCHEMBL6829815 | 0.88 | MEN1 (0.51) | MEN1KMT2ALTA4HALDH1A1MAPT | |
| SCHEMBL6256579 | 0.87 | LTA4H (0.51) | MEN1KMT2AAOC3LTA4HALDH1A1 | |
| SCHEMBL6829528 | 0.86 | KMT2A (0.50) | MEN1KMT2AAOC3LTA4HALDH1A1 | |
| SCHEMBL6829368 | 0.86 | KMT2A (0.53) | MEN1KMT2AAOC3LTA4HALDH1A1 | |
| SCHEMBL6659741 | 0.85 | MEN1 (0.49) | MEN1KMT2ALTA4HALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL6923246 | 0.84 | MEN1 (0.51) | MEN1KMT2ALTA4HALDH1A1MAPT | |
| SCHEMBL639305 | 0.84 | MAPT (0.49) | MEN1KMT2AAOC3ALDH1A1MAPT | |
| SCHEMBL639304 | 0.84 | MAPT (0.49) | MEN1KMT2AAOC3ALDH1A1MAPT | |
| SCHEMBL2044616 | 0.83 | ALDH1A1 (0.48) | MEN1KMT2AAOC3ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043921-A1 | NOVEL PROCESS FOR THE PREPARATION OF 4-ARYL-3-HYDROXYMETHYL-1-METHYLPIPERIDINES. | NATCO PHARMA LIMITED (IN) | 2004-05-27 | — | — | WO | disclosed |