SCHEMBL6256988

SCHEMBL6256988

C[Si]1(C)C(c2sc3ccccc3c2-c2ccccc2)=C(c2ccccc2)C(c2ccccc2)=C1c1sc2ccccc2c1-c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 4/20 0.47
▸ ITGA4 P13612 2/20 0.41
▸ HSP90AA1 P07900 2/20 0.41
▸ MEN1 O00255 2/20 0.40
▸ KMT2A Q03164 2/20 0.40
▸ TDP1 Q9NUW8 1/20 0.39
▸ PAX8 Q06710 1/20 0.37
▸ NAPEPLD Q6IQ20 1/20 0.36
▸ GPR3 P46089 1/20 0.35
▸ UBE2N P61088 1/20 0.35
▸ PTPN1 P18031 2/20 0.33
▸ FABP4 P15090 1/20 0.33
▸ FABP5 Q01469 1/20 0.33
▸ TNKS O95271 1/20 0.33
▸ TNKS2 Q9H2K2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6253915 0.88 L3MBTL1 (0.40) L3MBTL1ITGA4HSP90AA1MEN1KMT2A
SCHEMBL6254367 0.88 L3MBTL1 (0.47) L3MBTL1ITGA4HSP90AA1MEN1KMT2A
SCHEMBL6259140 0.85 L3MBTL1 (0.43) L3MBTL1ITGA4HSP90AA1MEN1KMT2A
SCHEMBL6256336 0.85 L3MBTL1 (0.48) L3MBTL1ITGA4HSP90AA1MEN1KMT2A
SCHEMBL6257040 0.84 ROCK1 (0.40) L3MBTL1ITGA4TDP1GPR3
SCHEMBL6254662 0.83 L3MBTL1 (0.46) L3MBTL1ITGA4HSP90AA1MEN1KMT2A
SCHEMBL6257244 0.81 PLA2G10 (0.36) L3MBTL1ITGA4GPR3PTPN1FABP4
SCHEMBL6254823 0.80 L3MBTL1 (0.41) L3MBTL1ITGA4HSP90AA1MEN1KMT2A
SCHEMBL6255390 0.78 L3MBTL1 (0.47) L3MBTL1ITGA4HSP90AA1MEN1KMT2A
SCHEMBL1294397 0.77 L3MBTL1 (0.68) L3MBTL1ITGA4HSP90AA1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1143538-B1 Organic electroluminescent element containing a silacyclopentadiene derivative CHISSO CORP (JP) 2005-09-14 — — EP disclosed
EP-0754691-B1 Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative CHISSO CORP (JP) 2003-11-19 — — EP disclosed
EP-1143538-A1 Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative Chisso Corporation (JP) 2001-10-10 — — EP disclosed
US-6051319-A Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative CHISSO CORPORATION (JP) 2000-04-18 — — US disclosed
US-5986121-A Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative CHISSO CORPORATION (JP) 1999-11-16 — — US disclosed
EP-0754691-A2 Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative CHISSO CORPORATION (JP) 1997-01-22 — — EP disclosed
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