SCHEMBL6253915

SCHEMBL6253915

Cc1cccc(C2=C(c3sc4ccccc4c3-c3ccccc3)[Si](C)(C)C(c3sc4ccccc4c3-c3ccccc3)=C2c2cccc(C)c2)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 4/20 0.40
▸ ITGA4 P13612 2/20 0.37
▸ NAPEPLD Q6IQ20 1/20 0.36
▸ HSP90AA1 P07900 2/20 0.36
▸ KMT2A Q03164 4/20 0.35
▸ MEN1 O00255 3/20 0.35
▸ TSHR P16473 2/20 0.35
▸ NPSR1 Q6W5P4 1/20 0.35
▸ TDP1 Q9NUW8 1/20 0.34
▸ RAB9A P51151 3/20 0.33
▸ SMN1; SMN2 Q16637 2/20 0.33
▸ SLC9A1 P19634 1/20 0.33
▸ LMNA P02545 1/20 0.33
▸ MAPT P10636 1/20 0.33
▸ IDE P14735 1/20 0.33
▸ CASP3 P42574 1/20 0.33
▸ SENP8 Q96LD8 1/20 0.33
▸ SENP7 Q9BQF6 1/20 0.33
▸ SENP6 Q9GZR1 1/20 0.33
▸ PAX8 Q06710 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6257837 0.90 L3MBTL1 (0.40) L3MBTL1ITGA4NAPEPLDHSP90AA1KMT2A
SCHEMBL6256988 0.88 L3MBTL1 (0.47) L3MBTL1ITGA4NAPEPLDHSP90AA1KMT2A
SCHEMBL6256327 0.87 ROCK1 (0.36) L3MBTL1KMT2AMEN1TSHRNPSR1
SCHEMBL6255888 0.84 PLA2G10 (0.35) L3MBTL1KMT2AMEN1TSHRNPSR1
SCHEMBL6257040 0.76 ROCK1 (0.40) L3MBTL1ITGA4TDP1
SCHEMBL6254367 0.76 L3MBTL1 (0.47) L3MBTL1ITGA4NAPEPLDHSP90AA1KMT2A
SCHEMBL6254825 0.75 RAB9A (0.44) L3MBTL1KMT2ATSHRNPSR1RAB9A
SCHEMBL6254738 0.75 APP (0.44) KMT2AMEN1
SCHEMBL6259140 0.75 L3MBTL1 (0.43) L3MBTL1ITGA4NAPEPLDHSP90AA1KMT2A
SCHEMBL6256336 0.74 L3MBTL1 (0.48) L3MBTL1ITGA4NAPEPLDHSP90AA1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1143538-B1 Organic electroluminescent element containing a silacyclopentadiene derivative CHISSO CORP (JP) 2005-09-14 — — EP disclosed
EP-0754691-B1 Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative CHISSO CORP (JP) 2003-11-19 — — EP disclosed
EP-1143538-A1 Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative Chisso Corporation (JP) 2001-10-10 — — EP disclosed
US-6051319-A Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative CHISSO CORPORATION (JP) 2000-04-18 — — US disclosed
US-5986121-A Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative CHISSO CORPORATION (JP) 1999-11-16 — — US disclosed
EP-0754691-A2 Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative CHISSO CORPORATION (JP) 1997-01-22 — — EP disclosed
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