Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 4/20 | 0.32 |
| ▸ | RAB9A | P51151 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9101137 | 0.85 | PDE3B (0.36) | PDE3BPDE3ACYP19A1 | |
| SCHEMBL18911211 | 0.83 | CYP19A1 (0.32) | CYP19A1 | |
| SCHEMBL18911044 | 0.83 | CYP19A1 (0.32) | CYP19A1 | |
| SCHEMBL18905397 | 0.80 | CYP19A1 (0.31) | PDE3BPDE3ACYP19A1 | |
| SCHEMBL18911080 | 0.79 | NQO1 (0.44) | NPC1RAB9AALDH1A1MAPTKDM4E | |
| SCHEMBL18905537 | 0.78 | SPHK1 (0.31) | — | |
| SCHEMBL18905436 | 0.77 | PDE3B (0.33) | PDE3BPDE3ACYP19A1 | |
| SCHEMBL151868 | 0.77 | NPC1 (0.35) | PDE3BPDE3ANPC1RAB9AALDH1A1 | |
| SCHEMBL18905440 | 0.76 | CYP19A1 (0.32) | CYP19A1 | |
| SCHEMBL18911042 | 0.76 | CYP2D6 (0.42) | CHRM2CHRM4CHRM5CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1268499-B1 | METHOD FOR POLYMERIZING POLAR SUBSTITUTED CYCLOALKENES | LANXESS DEUTSCHLAND GMBH (DE) | 2005-10-12 | — | — | EP | disclosed |
| US-6891007-B2 | Method for polymerizing polar substituted cycloalkenes | BAYER AKTIENGESELLSCHAFT (DE) | 2005-05-10 | — | — | US | disclosed |
| US-20030120011-A1 | Method for polymerizing polar substituted cycloalkenes | LANXESS DEUTSCHLAND GMBH (DE) | 2003-06-26 | — | — | US | disclosed |
| EP-1268499-A1 | METHOD FOR POLYMERIZING POLAR SUBSTITUTED CYCLOALKENES | Bayer Aktiengesellschaft (DE) | 2003-01-02 | — | — | EP | disclosed |
| EP-0829493-B1 | Use of nickel catalysts for polymerisation of cycloolefins | BAYER AG (DE) | 2002-08-14 | — | — | EP | disclosed |
| EP-0837079-B1 | Palladium-catalyst for polymerisation | BAYER AG (DE) | 2002-08-14 | — | — | EP | disclosed |
| US-6433112-B1 | COORDINATION POLYMERIZATION CATALYST | BAYER AKTIENGESELLSCHAFT (DE) | 2002-08-13 | — | — | US | disclosed |
| EP-1042336-B1 | PI-COMPLEX COMPOUNDS | BAYER AG (DE) | 2002-04-03 | — | — | EP | disclosed |
| WO-2001072760-A1 | METHOD FOR POLYMERIZING POLAR SUBSTITUTED CYCLOALKENES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-10-04 | — | — | WO | disclosed |
| US-6232413-B1 | USING ORGANOMETALLIC CATALYST | BAYER AKTIENGESELLSCHAFT (DE) | 2001-05-15 | — | — | US | disclosed |
| US-6156857-A | Method for producing cycloolefin (co)polymers for technical applications | BAYER AKTIENGESELLSCHAFT (DE) | 2000-12-05 | — | — | US | disclosed |
| EP-0909282-B1 | METHOD FOR PRODUCING CYCLOOLEFIN (CO)POLYMERS FOR TECHNICAL APPLICATIONS | BAYER AG (DE) | 2000-05-10 | — | — | EP | disclosed |
| US-6057466-A | POLYMERIZATION CATALYSTS | BAYER AKTIENGESELLSCHAFT (DE) | 2000-05-02 | — | — | US | disclosed |
| US-6040403-A | POLYMERIZATION OF CYCLOOLEFINS | BAYER AKTIENGESELLSCHAFT (DE) | 2000-03-21 | — | — | US | disclosed |
| EP-0837079-A2 | Palladium-catalyst for polymerisation | BAYER AG (DE) | 1998-04-22 | — | — | EP | disclosed |
| EP-0829493-A2 | Nickel catalyst for polymerisation | BAYER AG (DE) | 1998-03-18 | — | — | EP | disclosed |