SCHEMBL9101137

SCHEMBL9101137

C1=C(c2ccc(C3=CC4CCC3C4)cc2)C2CCC1C2

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PDE3B Q13370 1/20 0.36
PDE3A Q14432 1/20 0.36
CYP19A1 P11511 1/20 0.32
PTGS1 P23219 1/20 0.31
PTGS2 P35354 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4507498 0.89 NPC1 (0.34) PDE3BPDE3A
SCHEMBL17444935 0.85 PDE3B (0.34) PDE3BPDE3A
SCHEMBL31119160 0.85 CA2 (0.38) PDE3BPDE3A
SCHEMBL6257347 0.85 CHRM2 (0.36) PDE3BPDE3ACYP19A1
SCHEMBL18911080 0.81 NQO1 (0.44)
SCHEMBL18905537 0.80 SPHK1 (0.31)
SCHEMBL18911211 0.79 CYP19A1 (0.32) CYP19A1
SCHEMBL18905440 0.79 CYP19A1 (0.32) CYP19A1
SCHEMBL9022738 0.77 CHRM2 (0.49)
SCHEMBL18905391 0.76 PDE3B (0.31) PDE3BPDE3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2461420-B1 PHOTOELECTRIC ELEMENT PANASONIC CORP (JP) 2020-05-13 EP disclosed
US-8592807-B2 Photoelectric element PANASONIC CORPORATION (JP) 2013-11-26 US disclosed
US-20120187387-A1 PHOTOELECTRIC ELEMENT WASEDA UNIVERSITY (JP) 2012-07-26 US disclosed
EP-2461420-A1 PHOTOELECTRIC ELEMENT Panasonic Corporation (JP) 2012-06-06 EP disclosed