Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.62 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.62 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30379968 | 1.00 | TXNRD1 (0.62) | TXNRD1TXNRD3TXNRD2MAPTMEN1 | |
| SCHEMBL2962443 | 0.85 | MAPT (0.47) | TXNRD1TXNRD3TXNRD2MAPTL3MBTL1 | |
| SCHEMBL1744130 | 0.80 | TXNRD1 (0.56) | TXNRD1TXNRD3TXNRD2MAPTMEN1 | |
| SCHEMBL18936144 | 0.77 | CHRNB4 (0.43) | TXNRD1TXNRD3TXNRD2MAPTMEN1 | |
| SCHEMBL3860202 | 0.77 | MAPT (0.51) | TXNRD1TXNRD3TXNRD2MAPTMEN1 | |
| SCHEMBL6619488 | 0.75 | TXNRD1 (0.68) | TXNRD1TXNRD3TXNRD2MAPTMEN1 | |
| SCHEMBL30414974 | 0.75 | TXNRD1 (0.68) | TXNRD1TXNRD3TXNRD2MAPTMEN1 | |
| SCHEMBL11032479 | 0.75 | TXNRD1 (0.68) | TXNRD1TXNRD3TXNRD2MAPTMEN1 | |
| SCHEMBL8403300 | 0.75 | TXNRD1 (0.68) | TXNRD1TXNRD3TXNRD2MAPTMEN1 | |
| SCHEMBL4942788 | 0.74 | TXNRD1 (0.41) | TXNRD1TXNRD3TXNRD2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3392341-B1 | PROCESS FOR SHORTENING THE HYDROCARBON CHAIN OF A CARBOXYLIC ACID BY A PEROXYGENASE | CONSEJO SUPERIOR INVESTIGACION (ES) | 2021-03-10 | — | — | EP | disclosed |
| US-10501413-B2 | Inhibitors of the Notch transcriptional activation complex and methods for use of the same | UNIVERSITY OF MIAMI (US) | 2019-12-10 | — | — | US | disclosed |
| US-10465173-B2 | Polypeptides having peroxygenase activity and polynucleotides encoding same | NOVOZYMES A/S (DK) | 2019-11-05 | — | — | US | disclosed |
| US-10465172-B2 | Peroxygenase variants | NOVOZYMES A/S (DK) | 2019-11-05 | — | — | US | disclosed |
| EP-2906689-B1 | POLYPEPTIDES HAVING PEROXYGENASE ACTIVITY | NOVOZYMES AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| EP-2906690-B1 | POLYPEPTIDES HAVING PEROXYGENASE ACTIVITY | NOVOZYMES AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| EP-2661437-B1 | 2,4-DIAMINO-6,7-DIHYDRO-5H-PYRROLO[2,3]PYRIMIDINE DERIVATIVES AS FAK/Pyk2 INHIBITORS | CENTAURUS BIOPHARMA CO LTD (CN) | 2018-11-07 | — | — | EP | disclosed |
| EP-3392341-A1 | PROCESS FOR SHORTENING THE HYDROCARBON CHAIN OF A CARBOXYLIC ACID BY A PEROXYGENASE | Consejo Superior de Investigaciones Científicas (CSIC) (ES) | 2018-10-24 | — | — | EP | disclosed |
| CN-103748217-B | Polypeptide with peroxidase activity and the polynucleotides for encoding the polypeptide | NOVOZYMES A/S (DK) | 2018-08-31 | — | — | CN | disclosed |
| EP-2906688-B1 | POLYPEPTIDES HAVING PEROXYGENASE ACTIVITY | NOVOZYMES AS (DK) | 2018-08-29 | — | — | EP | disclosed |
| US-6166048-A | Pharmaceutical compositions for inhibition of cytokine production and secretion | TARGACEPT, INC. (US) | 2000-12-26 | — | — | US | disclosed |
| WO-2000062767-A2 | PHARMACEUTICAL COMPOSITIONS CONTAINING PYRIDINE OR PYRIMIDINE DERIVATES FOR INHIBITION OF CYTOKINE PRODUCTION AND SECRETION | TARGACEPT, INC. (US) | 2000-10-26 | — | — | WO | disclosed |
| EP-1042274-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS FOR USE | R.J. REYNOLDS TOBACCO COMPANY (US) | 2000-10-11 | — | — | EP | disclosed |
| WO-2000004036-A9 | PHOTOCLEAVABLE NUCLEOSIDE BASE | UNIV DUKE (US) | 2000-07-06 | — | — | WO | disclosed |
| WO-2000023418-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS FOR USE | R.J. REYNOLDS TOBACCO COMPANY (US) | 2000-04-27 | — | — | WO | disclosed |
| WO-2000004036-A1 | PHOTOCLEAVABLE NUCLEOSIDE BASE | DUKE UNIVERSITY (US) | 2000-01-27 | — | — | WO | disclosed |
| EP-0635483-B1 | Process for preparing nitroaniline derivatives | SUMITOMO CHEMICAL CO (JP) | 1997-10-22 | — | — | EP | disclosed |
| EP-0537518-B1 | Derivatives of 2,2-dihalobenzo(1,3)dioxoles substituted in the 4-position, methods for their preparation and their use | BAYER AG (DE) | 1996-04-17 | — | — | EP | disclosed |
| US-5281725-A | Derivatives of 2,2-dihalogenobenzo[1,3]dioxoles substituted in the 4-position, processes for their preparation and their use | BAYER AKTIENGESELLSCHAFT (DE) | 1994-01-25 | — | — | US | disclosed |
| EP-0537518-A1 | Derivatives of 2,2-dihalobenzo(1,3)dioxoles substituted in the 4-position, methods for their preparation and their use | BAYER AG (DE) | 1993-04-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10501413-B2 | Inhibitors of the Notch transcriptional activation complex and methods for use of the same | NOTCH1, CBFB, HES1 | TXNRD1 1705/4885TXNRD3 2486/4885TXNRD2 2995/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.