Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.56 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.56 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.56 |
| ▸ | CDK2 | P24941 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | TYMS | P04818 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2927803 | 0.81 | ALDH1A1 (0.46) | MAPTMEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL30379968 | 0.80 | TXNRD1 (0.62) | TXNRD1TXNRD3TXNRD2CDK2MAPT | |
| SCHEMBL6257481 | 0.80 | TXNRD1 (0.62) | TXNRD1TXNRD3TXNRD2CDK2MAPT | |
| SCHEMBL29626558 | 0.74 | ALDH1A1 (0.61) | MAPTMEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL187697 | 0.74 | ALDH1A1 (0.61) | MAPTMEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL29713706 | 0.72 | JAK2 (0.40) | TXNRD1TXNRD3TXNRD2CDK2MAPT | |
| SCHEMBL8316191 | 0.72 | ALDH1A1 (0.51) | TXNRD1TXNRD3TXNRD2MAPTMEN1 | |
| SCHEMBL9668748 | 0.72 | MEN1 (0.36) | TXNRD1TXNRD3TXNRD2CDK2MAPT | |
| SCHEMBL8403300 | 0.71 | TXNRD1 (0.68) | TXNRD1TXNRD3TXNRD2MAPTMEN1 | |
| SCHEMBL11032479 | 0.71 | TXNRD1 (0.68) | TXNRD1TXNRD3TXNRD2CDK2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2387564-A1 | BENZO ÝC¨PHENANTHRIDINES AS ANTIMICROBIAL AGENTS | Rutgers, The State University of New Jersey (US) | 2011-11-23 | — | — | EP | disclosed |
| US-8037884-B2 | Modular system for patient positioning during medical procedures | ALLEN MEDICAL SYSTEMS, INC. (US) | 2011-10-18 | — | — | US | disclosed |
| WO-2010083436-A1 | BENZO [C] PHENANTHRIDINES AS ANTIMICROBIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2010-07-22 | — | — | WO | disclosed |