Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 5/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.49 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.48 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6252797 | 0.97 | CYP11B2 (0.51) | CYP11B2CYP11B1CYP1A2CYP2A6CYP17A1 | |
| SCHEMBL6252563 | 0.86 | CYP1A2 (0.51) | CYP11B2CYP11B1CYP1A2CYP2A6CYP17A1 | |
| SCHEMBL6253426 | 0.85 | HSD17B1 (0.42) | CYP11B2CYP11B1CYP1A2CYP17A1HSD17B1 | |
| SCHEMBL6254404 | 0.84 | CYP11B2 (0.45) | CYP11B2CYP11B1CYP1A2CYP2A6CYP17A1 | |
| SCHEMBL6255660 | 0.84 | DYRK1A (0.44) | CYP1A2CYP2A6RAB9ANPC1MAPT | |
| SCHEMBL6255657 | 0.84 | NPC1 (0.45) | RAB9ANPC1KDM4EMAPTMEN1 | |
| SCHEMBL6254053 | 0.82 | CYP11B2 (0.54) | CYP11B2CYP11B1CYP1A2CYP2A6CYP17A1 | |
| SCHEMBL6258885 | 0.82 | CYP11B2 (0.48) | CYP11B2CYP11B1CYP1A2CYP2A6CYP17A1 | |
| SCHEMBL6252673 | 0.81 | CYP11B2 (0.47) | CYP11B2CYP11B1CYP1A2CYP2A6CYP17A1 | |
| SCHEMBL6257843 | 0.81 | CYP11B2 (0.47) | CYP11B2CYP11B1CYP1A2CYP2A6CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1143538-B1 | Organic electroluminescent element containing a silacyclopentadiene derivative | CHISSO CORP (JP) | 2005-09-14 | — | — | EP | disclosed |
| EP-0754691-B1 | Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative | CHISSO CORP (JP) | 2003-11-19 | — | — | EP | disclosed |
| EP-1143538-A1 | Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative | Chisso Corporation (JP) | 2001-10-10 | — | — | EP | disclosed |
| US-6051319-A | Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative | CHISSO CORPORATION (JP) | 2000-04-18 | — | — | US | disclosed |
| EP-0754691-A2 | Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative | CHISSO CORPORATION (JP) | 1997-01-22 | — | — | EP | disclosed |