Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | NAAA | Q02083 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 2/20 | 0.44 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.42 |
| ▸ | PRKCA | P17252 | 2/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8376617 | 1.00 | TSHR (0.47) | TSHRNAAAALDH1A1EPHX1FAAH | |
| SCHEMBL8380705 | 1.00 | TSHR (0.47) | TSHRNAAAALDH1A1EPHX1FAAH | |
| SCHEMBL10473435 | 1.00 | TSHR (0.47) | TSHRNAAAALDH1A1EPHX1FAAH | |
| SCHEMBL4334515 | 1.00 | TSHR (0.47) | TSHRNAAAALDH1A1EPHX1FAAH | |
| SCHEMBL1681497 | 0.97 | ALDH1A1 (0.52) | TSHRNAAAALDH1A1EPHX1FAAH | |
| SCHEMBL15910275 | 0.97 | ALDH1A1 (0.52) | TSHRNAAAALDH1A1EPHX1FAAH | |
| SCHEMBL8376851 | 0.97 | ALDH1A1 (0.52) | TSHRNAAAALDH1A1EPHX1FAAH | |
| SCHEMBL6259986 | 0.94 | FAAH (0.43) | TSHRNAAAALDH1A1EPHX1FAAH | |
| SCHEMBL6262611 | 0.94 | FAAH (0.43) | TSHRNAAAALDH1A1EPHX1FAAH | |
| SCHEMBL15903070 | 0.93 | FAAH (0.44) | TSHRNAAAALDH1A1FAAHZDHHC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6531143-B1 | Wax diesters containing alpha-hydroxy fatty acids esterified with fatty acids and higher alcohols | KANEBO, LIMITED (JP) | 2003-03-11 | — | — | US | claimed |
| EP-1084693-B1 | ALPHA-HYDROXY FATTY ACID DERIVATIVES AND COMPOSITION FOR EXTERNAL USE CONTAINING THE SAME | KANEBO COSMETICS INC (JP) | 2005-10-05 | — | — | EP | disclosed |
| US-6531143-B1 | Wax diesters containing alpha-hydroxy fatty acids esterified with fatty acids and higher alcohols | KANEBO, LIMITED (JP) | 2003-03-11 | — | — | US | disclosed |
| EP-1084693-A1 | $g(a)-HYDROXY FATTY ACID DERIVATIVES AND COMPOSITION FOR EXTERNAL USE CONTAINING THE SAME | Kanebo Limited (JP) | 2001-03-21 | — | — | EP | disclosed |