Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4876747 | 1.00 | ADK (0.53) | ADKALDH1A1HTTNPC1RXFP1 | |
| Acetic Acid SCHEMBL4894479 | 0.98 | ADK (0.52) | ADKALDH1A1HTTNPC1RXFP1 | |
| SCHEMBL4864949 | 0.87 | ADK (0.67) | ADKALDH1A1HTTNPC1RXFP1 | |
| SCHEMBL4876854 | 0.84 | ADK (0.72) | ADKALDH1A1HTTNPC1MAPT | |
| Acetic Acid SCHEMBL6254291 | 0.82 | ADK (0.70) | ADKALDH1A1HTTNPC1MAPT | |
| Acetic Acid SCHEMBL4870516 | 0.82 | ADK (0.70) | ADKALDH1A1HTTNPC1MAPT | |
| Acetic Acid SCHEMBL4914055 | 0.78 | ALDH1A1 (0.39) | ALDH1A1RXFP1 | |
| SCHEMBL4875665 | 0.76 | ADK (0.52) | ADKALDH1A1 | |
| SCHEMBL4877505 | 0.71 | ADK (0.64) | ADKALDH1A1HTTNPC1MAPT | |
| SCHEMBL12870497 | 0.71 | ADK (0.64) | ADKALDH1A1HTTNPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1534726-A2 | NUCLEOSIDE COMPOUNDS AND THEIR USE FOR TREATING CANCER AND DISEASES ASSOCIATED WITH SOMATIC MUTATIONS | PTC Therapeutics, Inc. (US) | 2005-06-01 | — | — | EP | disclosed |
| WO-2004009609-A2 | NUCLEOSIDE COMPOUNDS AND THEIR USE FOR TREATING CANCER AND DISEASES ASSOCIATED WITH SOMATIC MUTATIONS | PTC THERAPEUTICS, INC. (US) | 2004-01-29 | — | — | WO | disclosed |