SCHEMBL6258348

SCHEMBL6258348

CC(C)(C)OC(=O)N1CCN(c2ccc(N3CC(CN)OC3=O)cn2)CC1

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
DDB1 Q16531 1/20 0.47
CRBN Q96SW2 1/20 0.47
GPR119 Q8TDV5 6/20 0.47
MAP4K4 O95819 1/20 0.46
F10 P00742 2/20 0.44
ADK P55263 1/20 0.44
CKS1B P61024 2/20 0.43
SKP1 P63208 2/20 0.43
SKP2 Q13309 2/20 0.43
RET P07949 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
MEN1 O00255 1/20 0.43
MAPT P10636 1/20 0.43
TSHR P16473 1/20 0.43
KMT2A Q03164 1/20 0.43
WNT3A P56704 1/20 0.41
HPGD P15428 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10151460 0.93 F10 (0.44) DDB1CRBNGPR119MAP4K4F10
SCHEMBL14261333 0.92 DDB1 (0.49) DDB1CRBNGPR119MAP4K4F10
SCHEMBL2088197 0.87 F10 (0.49) DDB1CRBNGPR119MAP4K4F10
SCHEMBL6238084 0.87 F10 (0.49) DDB1CRBNGPR119MAP4K4F10
SCHEMBL6257514 0.86 F10 (0.47) DDB1CRBNGPR119MAP4K4F10
SCHEMBL10151464 0.85 MAOA (0.45) DDB1CRBNGPR119MAP4K4F10
SCHEMBL2088196 0.84 DDB1 (0.45) DDB1CRBNGPR119MAP4K4ADK
SCHEMBL27592184 0.84 DDB1 (0.45) DDB1CRBNGPR119MAP4K4ADK
SCHEMBL80077 0.81 MAOB (0.58) F10
SCHEMBL3396418 0.81 MAOB (0.58) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005003087-A2 OXAZOLE DERIVATIVES AS ANTIBACTERIAL AGENTS ORCHID CHEMICALS AND PHARMACEUTICALS LTD. (IN) 2005-01-13 WO disclosed
WO-2004009587-A1 OXAZOLIDINONE DERIVATIVES AS ANTIBACTERIAL AGENTS ORCHID CHEMICALS & PHARMACEUTICALS LTD (IN) 2004-01-29 WO disclosed